Sophie B. M.
- Country
- The Netherlands
- Department
- Hematology
Research Overview
Data & Insights
Has run more than one trial at 4 of 60 partner sites.
Specializations
Hematologic malignancies
The investigator is engaged in clinical research across acute myeloid leukemia, myelodysplastic syndromes, multiple myeloma, and lymphoma, with interest in treatment-resistant and relapsed disease, transplant-related care, and cellular therapy.
- Acute myeloid leukemia
- Myelodysplastic syndromes
- Multiple myeloma
- Diffuse large B-cell lymphoma
Research activity also includes myelofibrosis, chronic lymphocytic leukemia, and Hodgkin lymphoma, reflecting a strong therapeutic focus on hematologic cancer innovation.
Solid tumors and thoracic oncology
Clinical trial involvement spans non-small cell lung cancer, small cell lung cancer, head and neck squamous cell carcinoma, breast cancer, and urothelial cancer, with attention to advanced, metastatic, and resectable settings.
- Non-small cell lung cancer
- Small cell lung cancer
- Head and neck squamous cell carcinoma
- Urothelial cancer
Additional interests include pancreatic cancer, colorectal cancer, gastric cancer, and melanoma, covering multiple oncologic therapeutic domains.
Immune-mediated and inflammatory disease
The investigator is involved in studies of rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, Crohn's disease, and ulcerative colitis, indicating a broad interest in autoimmune and chronic inflammatory disorders.
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Systemic sclerosis
- Inflammatory bowel disease
Work also extends to myositis, vasculitis, and psoriasis, supporting therapeutic development in immune dysregulation.
Cardiovascular and thrombotic disease
Research activity includes coronary artery disease, heart failure, atrial fibrillation, myocardial infarction, and stroke, with emphasis on prevention and treatment of major cardiovascular events.
- Coronary artery disease
- Heart failure
- Atrial fibrillation
- Ischemic stroke
Interest also includes pulmonary arterial hypertension, venous thromboembolism, and cardiomyopathy, reflecting a cardiovascular therapeutic portfolio.
Metabolic, hepatic, and renal disorders
The investigator is active in trials addressing primary sclerosing cholangitis, primary biliary cholangitis, metabolic dysfunction-associated steatotic liver disease, chronic kidney disease, and IgA nephropathy.
- Primary sclerosing cholangitis
- Metabolic dysfunction-associated steatotic liver disease
- Chronic kidney disease
- IgA nephropathy
Additional work includes diabetes, obesity, and familial hypercholesterolemia, highlighting interest in long-term metabolic and organ-protective therapies.
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