Sophia R.
- Country
- France
- Department
- Oncologie medicale
Research Overview
Data & Insights
Has run more than one trial at 0 of 4 partner sites.
Specializations
Haematologic Malignancies
The investigator is involved in clinical research across acute myeloid leukemia, myelodysplastic syndromes, and overlapping myeloid disorders, with additional interest in acute lymphoblastic leukemia, chronic lymphocytic leukemia, and aggressive B-cell lymphomas.
- Acute myeloid leukemia
- Myelodysplastic syndromes
- B-cell lymphomas
- Acute lymphoblastic leukemia
Research activity also extends to multiple myeloma, myelofibrosis, and other relapsed or refractory blood cancers, reflecting a strong therapeutic focus on difficult-to-treat haematologic disease.
Lung Cancer and Thoracic Oncology
A major area of interest is non-small cell lung cancer, including advanced, metastatic, and biomarker-defined disease, alongside small cell lung cancer and selected thoracic malignancies such as mesothelioma.
- Non-small cell lung cancer
- Small cell lung cancer
- Mesothelioma
- Thoracic solid tumors
The investigator’s work includes treatment strategies for advanced thoracic cancers with molecular alterations such as EGFR, ALK, ROS1, RET, and HER2 aberrations.
Breast and Gynaecologic Cancers
Clinical research activity includes breast cancer across hormone receptor-positive, HER2-positive, HER2-low, and triple-negative breast cancer settings, with attention to both early and metastatic disease.
- Breast cancer
- Triple-negative breast cancer
- Ovarian cancer
- Endometrial cancer
Additional involvement covers cervical cancer, vulvar cancer, fallopian tube cancer, and primary peritoneal cancer, with a clear emphasis on advanced and recurrent gynaecologic malignancies.
Gastrointestinal and Hepatobiliary Oncology
The investigator is active in studies of colorectal cancer, gastric cancer, pancreatic cancer, and biliary tract cancer, spanning locally advanced, metastatic, and biomarker-selected disease.
- Colorectal cancer
- Pancreatic cancer
- Biliary tract cancer
- Gastric cancer
Research interests also include hepatocellular carcinoma, esophageal cancer, and gastrointestinal stromal tumor, with attention to molecularly defined gastrointestinal malignancies.
Genitourinary, Sarcoma, and Molecularly Targeted Solid Tumors
Another prominent area is renal cell carcinoma, urothelial carcinoma, and prostate cancer, together with a broad portfolio of soft tissue sarcoma, melanoma, and other advanced solid tumors.
- Renal cell carcinoma
- Urothelial carcinoma
- Prostate cancer
- Soft tissue sarcoma
The investigator is also involved in research on molecularly selected cancers involving KRAS, MTAP, FGFR, IDH, and HER2 alterations, as well as rare and refractory solid tumors.
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