Sofie O.
- Country
- Belgium
- Department
- Department of Critical Care
Research Overview
Data & Insights
Has run more than one trial at 0 of 8 partner sites.
Specializations
Cardiovascular Critical Care
Focuses on life‑threatening cardiac conditions managed in intensive settings, including ischemic events, heart failure phenotypes, arrhythmias, and vascular risk modulation.
- Acute coronary syndrome
- Heart failure
- Atrial fibrillation
- Atherosclerotic cardiovascular disease
- Hypertension
Therapeutic strategies aim to stabilize hemodynamics and reduce recurrent cardiovascular events.
Renal and Metabolic Critical Care
Addresses renal dysfunction and metabolic derangements encountered in critically ill patients, ranging from acute injury to chronic glomerular disease and fatty liver syndromes.
- Acute kidney injury
- Chronic kidney disease
- Immunoglobulin A nephropathy
- Non‑alcoholic steatohepatitis
- Obesity
Interventions target preservation of renal function and metabolic homeostasis.
Pulmonary and Respiratory Critical Care
Specializes in severe pulmonary disorders and infectious respiratory complications that require intensive support.
- Chronic obstructive pulmonary disease
- Severe community‑acquired pneumonia
- Respiratory syncytial virus infection
- Bronchopulmonary dysplasia
- Pulmonary hypertension
Management includes ventilatory strategies and antiviral/antimicrobial therapies.
Oncologic and Hematologic Critical Care
Encompasses oncologic emergencies and hematologic crises managed in critical care environments.
- Acute myeloid leukemia
- Relapsed or refractory multiple myeloma
- Prostate cancer with metastatic progression
- Muscle‑invasive urothelial carcinoma
- Melanoma
Therapeutic focus includes rapid disease control and mitigation of treatment‑related toxicities.
Peri‑operative and Surgical Critical Care
Concentrates on peri‑operative critical care, emphasizing cardiac and non‑cardiac surgery, anticoagulation reversal, and sepsis‑related organ injury.
- Cardiac surgery‑associated acute kidney injury
- Anticoagulation reversal for factor Xa inhibitors
- Sepsis‑associated acute kidney injury
- Major thoracic surgery
- Post‑operative bleeding management
Goals are to optimize recovery and prevent postoperative complications.
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