Smaïl H. R.
- Country
- France
- Department
- Dermatology department
Research Overview
Data & Insights
Has run more than one trial at 3 of 63 partner sites.
Specializations
Inflammatory Dermatology and Autoimmune Skin Disease
Clinical research activity includes conditions centered on chronic inflammatory and immune-mediated skin disorders, with particular attention to atopic dermatitis, psoriasis, hidradenitis suppurativa, prurigo nodularis, and vitiligo. The investigator is also involved in studies addressing severe cutaneous immune reactions and connective tissue disease-related skin involvement.
- Atopic dermatitis
- Psoriasis
- Hidradenitis suppurativa
- Prurigo nodularis
- Vitiligo
Additional interests extend to bullous pemphigoid, pemphigus, and other complex inflammatory dermatoses requiring targeted therapeutic innovation.
Cutaneous Autoimmunity and Systemic Inflammatory Disease
The investigator’s landscape includes dermatologic manifestations of broader immune disorders, especially cutaneous lupus erythematosus, systemic lupus erythematosus, systemic sclerosis, dermatomyositis, and Sjögren’s disease. This work also overlaps with vasculitic and autoinflammatory presentations that affect the skin and soft tissues.
- Cutaneous lupus erythematosus
- Systemic lupus erythematosus
- Systemic sclerosis
- Dermatomyositis
- Sjögren’s disease
Research activity also touches vasculitis, Raynaud phenomenon, and other inflammatory syndromes with dermatologic expression.
Genodermatoses and Rare Skin Disorders
Another major area of interest is rare and inherited dermatologic disease, including epidermolysis bullosa, inflammatory epidermal genodermatoses, Netherton syndrome, x-linked hypohidrotic ectodermal dysplasia, and palmoplantar pustulosis. The investigator is engaged in research relevant to severe barrier defects, blistering disease, and congenital skin fragility.
- Epidermolysis bullosa
- Inflammatory epidermal genodermatoses
- Netherton syndrome
- X-linked hypohidrotic ectodermal dysplasia
- Palmoplantar pustulosis
This domain reflects a focus on rare dermatologic conditions where precision therapies and specialized clinical management are especially important.
Skin Lymphoma and Oncodermatology
Clinical trial involvement also extends to malignant and premalignant skin disease, with emphasis on cutaneous T-cell lymphoma, mycosis fungoides, Sézary syndrome, cutaneous squamous cell carcinoma, and melanoma. These activities place the investigator within the therapeutic interface of dermatology and oncology.
- Cutaneous T-cell lymphoma
- Mycosis fungoides
- Sézary syndrome
- Cutaneous squamous cell carcinoma
- Melanoma
There is also interest in actinic keratosis and other skin neoplasms that require early intervention and evolving targeted treatment options.
Immune-Mediated Mucocutaneous Disease
The investigator is further involved in studies of chronic mucocutaneous inflammation, including chronic spontaneous urticaria, recurrent aphthous stomatitis, erythema multiforme, and severe mucous membrane pemphigoid. This area also includes disorders with significant impact on quality of life and persistent inflammatory burden.
- Chronic spontaneous urticaria
- Recurrent aphthous stomatitis
- Erythema multiforme
- Mucous membrane pemphigoid
- Severe mucocutaneous inflammation
Research in this field supports therapeutic development for difficult-to-control inflammatory disease affecting the skin and mucosa.
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