Sine L.
- Country
- Denmark
- Department
- The Hans Christian Andersen Childrens Hospital
Research Overview
Data & Insights
Has run more than one trial at 0 of 42 partner sites.
Specializations
Pediatric Oncology
The investigator concentrates on malignancies affecting children and adolescents, including central nervous system tumors and solid organ cancers.
- Advanced solid tumors in pediatric patients
- Diffuse intrinsic pontine glioma
- Pediatric medulloblastoma subtypes
- High‑risk neuroblastoma
Research is conducted through the Odense University Hospital pediatric oncology unit.
Infectious Diseases
Clinical investigations address bacterial, viral, and mycobacterial infections across age groups.
- Nontuberculous mycobacterial lung disease
- Severe COVID‑19 manifestations
- Chronic hepatitis B infection
- Complicated urinary tract infections
Collaboration with the infectious disease department at Odense University Hospital supports patient enrollment.
Cardiovascular & Metabolic Disorders
Studies target atherosclerotic cardiovascular disease, heart failure, and metabolic risk factors.
- Atherosclerotic cardiovascular disease with elevated lipoprotein(a)
- Heart failure with preserved ejection fraction
- Atrial fibrillation management post‑surgery
- Hyperlipidemia and dyslipidemia
Utilizes the cardiac care facilities at the affiliated research site.
Autoimmune & Inflammatory Conditions
Research includes systemic autoimmune diseases and chronic inflammatory disorders.
- Systemic lupus erythematosus
- Antineutrophil cytoplasmic antibody‑associated vasculitis
- Atopic dermatitis
- Chronic inflammatory demyelinating polyneuropathy
Patient recruitment leverages multidisciplinary clinics at the children's hospital.
Rare & Metabolic Diseases
Investigator explores rare protein deposition and metabolic syndromes.
- Light chain (AL) amyloidosis
- Transthyretin amyloid cardiomyopathy
- Klinefelter syndrome (47,XXY)
- Adynamic bone disorder
Specialized diagnostics are performed in partnership with the university hospital laboratory.
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