Sieneke H.
- Country
- The Netherlands
- Department
- Oncology
Research Overview
- Evaluation of Bintrafusp Alfa Combined with Chemoradiation in Esophageal Squamous Cell Carcinoma: A Feasibility Study
- Evaluation of Trastuzumab and Pertuzumab Addition to Neoadjuvant Chemoradiation in Resectable HER2-Positive Esophageal Adenocarcinoma
- Phase 2 Study of Fulvestrant and Alpelisib in PIK3CA-Mutated HR+ HER2- Advanced Breast Cancer Post-Fulvestrant Progression
Data & Insights
Has run more than one trial at 24 of 52 partner sites.
Specializations
Oncology - Breast and Gastrointestinal
The investigator specializes in treating hormone receptor-positive breast cancer and gastrointestinal malignancies, with particular emphasis on personalized therapeutic approaches.
- Advanced breast cancer treatment with targeted therapies
- Esophageal and gastric cancer management
- HER2-positive adenocarcinoma treatment
Expertise extends to treating peritoneal carcinomatosis in gastric cancer patients using advanced surgical techniques.
Hematologic Oncology
Focused on treating multiple myeloma and non-Hodgkin lymphoma through targeted therapeutic approaches and precision medicine strategies.
- Advanced solid tumor management
- Genomic-guided therapy selection
- Targeted anti-cancer treatments
Implements personalized treatment protocols based on genomic and protein expression variants.
Metabolic and Renal Medicine
Specializes in managing severe hypertriglyceridemia and complex chronic kidney disease conditions.
- Kidney failure prevention and management
- Heart failure complications in renal disease
- Metabolic disorder treatments
Focuses on integrated care approaches for patients with concurrent cardiovascular and renal conditions.
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