Sied K.
- Country
- Germany
- Department
- Clinical Neurooncology, Department of Neurology
Research Overview
- ONC201 for the Treatment of Newly Diagnosed H3 K27M-mutant Diffuse Glioma Following Completion of Radiotherapy: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study (The ACTION Study)
- Evaluation of CVGBM Vaccine Efficacy and Safety in Patients with Surgically Resected Glioblastoma or Astrocytoma with Unmethylated Glioblastoma Signature
- Evaluation of SonoCloud-9 with Carboplatin Versus Lomustine or Temozolomide in First Recurrence Glioblastoma Post-Resection: A Randomized, Open-Label Trial
Data & Insights
Has run more than one trial at 40 of 106 partner sites.
Specializations
Primary Brain Tumors
This investigator specializes in treating various forms of glioblastoma, including newly diagnosed and recurrent cases. Their research encompasses innovative therapeutic approaches for both unmethylated MGMT promoter glioblastoma and standard presentations.
- Newly diagnosed glioblastoma management
- Recurrent glioblastoma treatment strategies
- MGMT promoter status considerations
The investigator explores combination therapies including Tumor Treating Fields and immunotherapy approaches.
Specialized Glioma Research
The investigator focuses on treating distinct molecular subtypes of gliomas, particularly those with specific genetic mutations such as H3 K27M-mutant diffuse glioma and IDH1/IDH2 mutated gliomas.
- Grade 2 glioma treatment
- Molecular targeted therapies
- Post-surgical treatment strategies
Their work includes evaluation of novel targeted treatments for specific genetic alterations in brain tumors.
Advanced Treatment Modalities
The investigator explores innovative treatment approaches including personalized immunotherapy and targeted molecular therapies. Their research extends to medulloblastoma in post-pubertal and adult patients.
- Vaccine-based therapies
- Blood-brain barrier modulation
- Age-adapted treatment protocols
Treatment strategies include novel drug delivery systems and personalized therapeutic approaches based on molecular signatures.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.