SEVERINE N.
- Country
- France
- Department
- CHIRURGIE DIGESTIVE
Research Overview
Data & Insights
Has run more than one trial at 0 of 32 partner sites.
Specializations
Gastrointestinal Oncology
Focuses on malignant diseases of the digestive tract, including colorectal cancer, pancreatic cancer, and gastric cancer.
- advanced biliary tract carcinoma
- metastatic colorectal cancer
- pancreatic ductal adenocarcinoma
- gastric adenocarcinoma
- HER2‑positive solid tumors
Research aims to improve survival outcomes through novel therapeutic strategies.
Hepatology and Liver Failure
Addresses liver cirrhosis, acute‑on‑chronic liver failure, and hepatocellular carcinoma.
- acute‑on‑chronic liver failure
- non‑alcoholic steatohepatitis (NASH)
- hepatocellular carcinoma
- portal hypertension
- liver transplantation complications
Efforts include targeting metabolic pathways and fibrosis regression.
Autoimmune and Inflammatory Disorders
Investigates systemic autoimmune conditions such as systemic lupus erythematosus and primary Sjögren’s syndrome.
- systemic lupus erythematosus
- primary Sjögren’s syndrome
- dermatomyositis
- sarcoidosis
- giant cell arteritis
Therapeutic development centers on immune modulation.
Neurological and Neuromuscular Conditions
Covers peripheral neuropathy, amyotrophic lateral sclerosis, and multiple sclerosis.
- anti‑MAG neuropathy
- amyotrophic lateral sclerosis
- multiple sclerosis
- peripheral neuropathy
- neuroinflammation in critical care
Focus includes neuroprotective agents and disease‑modifying therapies.
Infectious Diseases and Transplant Immunology
Encompasses HIV‑1 infection, hepatitis B virus, and post‑transplant lymphoproliferative disorders.
- HIV‑1 infection
- hepatitis B virus
- post‑transplant lymphoproliferative disease
- cytomegalovirus reactivation
- antiviral resistance
Studies aim to enhance antiviral efficacy and graft outcomes.
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