Serio A. B.
- Country
- Spain
- Department
- Pneumonology
Research Overview
- Phase Ib Dose-Ranging Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of HS235 Versus Placebo in Combination with Background Therapy in Pulmonary Arterial Hypertension
- Efficacy and Safety of IKT-001 in Adults with WHO Group 1 Pulmonary Arterial Hypertension: An Adaptive, Randomized, Double-Blind, Placebo-Controlled Trial
- Open-Label Extension Study of Inhaled Treprostinil Palmitil Powder for Safety and Tolerability in Pulmonary Hypertension Associated with Interstitial Lung Disease
Data & Insights
Has run more than one trial at 100 of 135 partner sites.
Specializations
Respiratory Infections and Mycobacterial Diseases
Investigation of severe lung infections with emphasis on atypical pathogens and hospital‑acquired etiologies.
- Non‑tuberculous Mycobacterial lung disease
- Bronchiectasis with chronic Pseudomonas colonization
- Ventilator‑associated pneumonia
Research integrates microbiological profiling and host‑response modulation to reduce morbidity and mortality.
Obstructive Airway Diseases
Therapeutic exploration in chronic airflow limitation and allergic airway inflammation.
- Chronic Obstructive Pulmonary Disease
- Asthma
- Acute exacerbations of COPD
Focus includes phenotype‑directed interventions and strategies to prevent acute worsening.
Interstitial Lung Disease and Pulmonary Fibrosis
Study of progressive fibrotic lung disorders and novel antifibrotic approaches.
- Idiopathic pulmonary fibrosis
- Non‑alcoholic steatohepatitis‑related lung involvement
- Interstitial lung disease associated with connective‑tissue disorders
Efforts aim to identify early biomarkers and improve disease‑modifying treatment options.
Acute Respiratory Failure and Critical Care Pulmonology
Management of life‑threatening respiratory compromise in intensive settings.
- Acute hypoxemic respiratory failure
- Acute respiratory distress syndrome
- COVID‑19 severe pneumonia
Investigations include ventilation strategies, adjunctive therapies and outcome optimization.
Pulmonary Vascular Disease and Pulmonary Hypertension
Targeted research on disorders of the pulmonary circulation and right‑heart interaction.
- Pulmonary arterial hypertension
- Chronic thromboembolic pulmonary hypertension
- Right‑ventricular dysfunction in lung disease
Studies evaluate hemodynamic profiling and emerging vasodilator therapies.
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