Sergio S.
- Country
- Italy
- Department
- U.O. Ematologia
Research Overview
- Phase 3 Randomized Trial of Cytarabine, Midostaurin, and Daunorubicin Hydrochloride in FLT3-Mutated Acute Myeloid Leukemia with Peripheral Blast Clearance
- Prospective Study on Nilotinib Versus Imatinib with Nilotinib Switch in BCR-ABL+ Chronic Myeloid Leukemia in Chronic Phase
- Efficacy of Venetoclax and Decitabine in Acute Myeloid Leukemia Secondary to Myeloproliferative Neoplasms Unfit for Intensive Chemotherapy
Data & Insights
Has run more than one trial at 84 of 182 partner sites.
Specializations
Leukemia Research
Specializes in investigating therapeutic approaches for various forms of leukemia, with particular focus on Acute Myeloid Leukemia (AML) and Chronic Myeloid Leukemia (CML). The investigator studies novel combination treatments and targeted therapies.
- FLT3-mutated AML treatment optimization
- BCR-ABL+ therapy responses
- Philadelphia Chromosome-Positive ALL treatment
Explores innovative therapeutic combinations including decitabine, venetoclax, and targeted agents for leukemia treatment.
Multiple Myeloma Studies
Conducts research in multiple myeloma treatment with a focus on novel therapeutic combinations for transplant-ineligible patients. Investigates targeted antibody therapies and immunomodulatory approaches.
- Elranatamab combination therapy
- Daratumumab-based regimens
- Lenalidomide combinations
Evaluates treatment efficacy through minimal residual disease assessment and progression-free survival metrics.
Myelodysplastic Syndromes
Focuses on therapeutic interventions for high-risk myelodysplastic syndromes and specialized treatment approaches for del5q MDS. Studies include hypomethylating agents and stem cell transplantation strategies.
- Luspatercept for anemia treatment
- Hematopoietic stem cell transplantation
- Treatment of transfusion-dependent patients
Investigates novel approaches for managing treatment-resistant forms of MDS.
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