Sergio R. M.
- Country
- Spain
- Department
- Rheumatology
Research Overview
- Long-Term Safety and Tolerability Assessment of Dapirolizumab Pegol in Patients with Systemic Lupus Erythematosus: A Multicenter, Open-Label Extension Study
- Evaluation of Dapirolizumab Pegol Efficacy and Safety in Moderately to Severely Active Systemic Lupus Erythematosus: A Randomized, Double-Blind, Placebo-Controlled Study
- Evaluation of the Efficacy and Safety of GLPG3667 in Adults with Active Systemic Lupus Erythematosus: A Randomized, Double-Blind, Placebo-Controlled Study
Data & Insights
Has run more than one trial at 117 of 260 partner sites.
Specializations
Systemic autoimmune rheumatic diseases
Clinical research activity in rheumatology is centered on inflammatory and immune-mediated disorders, with a strong focus on systemic lupus erythematosus, rheumatoid arthritis, psoriatic arthritis, Sjögren’s syndrome, idiopathic inflammatory myopathy, and axial spondyloarthritis.
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Psoriatic arthritis
- Sjögren’s syndrome
- Idiopathic inflammatory myopathy
Interest also extends to cutaneous lupus erythematosus, ulcerative colitis, and other systemic inflammatory conditions linked to immune dysregulation.
Autoimmune disease therapeutics
The therapeutic landscape includes biologic and targeted approaches for controlling disease activity in lupus and related immune disorders, with attention to agents aimed at improving clinical response, symptom control, and long-term disease management.
- Belimumab
- Upadacitinib
- Dapirolizumab pegol
- Afimetoran
- GLPG3667
Research also covers efgartigimod and other immunomodulatory strategies for refractory or persistent autoimmune activity.
Solid tumors in thoracic and genitourinary oncology
Oncology involvement is broad, with repeated focus on non-small cell lung cancer, small cell lung cancer, endometrial cancer, ovarian cancer, breast cancer, and bladder cancer, including advanced, metastatic, and biomarker-defined disease.
- Non-small cell lung cancer
- Endometrial cancer
- Ovarian cancer
- Breast cancer
- Bladder cancer
Key interests include EGFR-mutated, MET-altered, and HER2-positive disease, as well as perioperative and metastatic treatment strategies.
Hematologic malignancies
Clinical trial activity also includes multiple blood cancers, particularly multiple myeloma, chronic lymphocytic leukemia, follicular lymphoma, diffuse large B-cell lymphoma, and small lymphocytic lymphoma.
- Multiple myeloma
- Chronic lymphocytic leukemia
- Follicular lymphoma
- Diffuse large B-cell lymphoma
- Small lymphocytic lymphoma
Research interests extend to myelodysplastic syndromes and relapsed or refractory disease settings across lymphoid and plasma-cell malignancies.
Cardiometabolic, infectious, and organ-specific conditions
The investigator is involved in studies spanning heart failure, dyslipidemia, atherosclerotic cardiovascular disease, chronic kidney disease, and resistant hypertension, alongside selected infectious and organ-specific disorders.
- Heart failure
- Dyslipidemia
- Atherosclerotic cardiovascular disease
- Chronic kidney disease
- Infectious diseases
Additional interests include COVID-19, severe bacterial infections, corneal trophic ulcers, and progressive fibrosing interstitial lung disease.
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