Sergio R. C.
- Country
- Spain
- Department
- Hematology
Research Overview
- A Multicenter, Open-label, Phase 2 Dose Escalation and Confirmation, and Efficacy Expansion Study of Zilovertamab Vedotin (MK-2140) in Combination with R-CHP in Participants with DLBCL (waveLINE)
- An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial
- Phase 3 Randomized Double‑Blind Trial of Orelabrutinib Combined with Rituximab and Bendamustine versus Rituximab‑Bendamustine in Treatment‑Naïve Mantle Cell Lymphoma
Data & Insights
Has run more than one trial at 322 of 503 partner sites.
Specializations
Acute Myeloid Leukemia and Other Myeloid Malignancies
Clinical activity in acute myeloid leukemia, myelodysplastic syndromes, myeloproliferative neoplasms, and myelofibrosis, with interest in relapsed, refractory, and high-risk disease settings as well as measurable residual disease assessment.
- Acute myeloid leukemia
- Myelodysplastic syndrome
- Myeloproliferative neoplasm
- Myelofibrosis
- Acute leukemia
Also involved in acute lymphoblastic leukemia, high-risk myelodysplastic neoplasms, and hematopoietic stem cell transplantation-related complications.
Lymphoma and B-Cell Hematologic Malignancies
Research spans diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, chronic lymphocytic leukemia, small lymphocytic lymphoma, and other non-Hodgkin lymphoma subtypes, including aggressive and relapsed/refractory presentations.
- Diffuse large B-cell lymphoma
- Follicular lymphoma
- Mantle cell lymphoma
- Chronic lymphocytic leukemia
- Non-Hodgkin lymphoma
Therapeutic interest extends to Hodgkin lymphoma, peripheral T-cell lymphoma, cutaneous T-cell lymphoma, and cell therapy approaches for lymphoid cancers.
Solid Tumor Oncology
Active involvement in a broad range of solid tumors, with strong emphasis on non-small cell lung cancer, head and neck squamous cell carcinoma, breast cancer, colorectal cancer, gastric cancer, and pancreatic cancer.
- Non-small cell lung cancer
- Head and neck squamous cell carcinoma
- Breast cancer
- Colorectal cancer
- Pancreatic ductal adenocarcinoma
Additional interest includes hepatocellular carcinoma, biliary tract cancer, urothelial carcinoma, ovarian cancer, melanoma, and sarcoma.
Renal, Urologic, and Metabolic Kidney Disease
Clinical research covers chronic kidney disease, immunoglobulin A nephropathy, focal segmental glomerulosclerosis, autosomal dominant polycystic kidney disease, and Alport syndrome, alongside kidney-related complications in systemic disease.
- Chronic kidney disease
- Immunoglobulin A nephropathy
- Focal segmental glomerulosclerosis
- Autosomal dominant polycystic kidney disease
- Alport syndrome
Urologic interests include urothelial carcinoma, non-muscle invasive bladder cancer, upper tract urothelial carcinoma, and localized bladder cancer.
Immune-Mediated, Respiratory, and Neurologic Disorders
Work also includes asthma, chronic obstructive pulmonary disease, chronic rhinosinusitis with nasal polyps, hidradenitis suppurativa, and inflammatory bowel disease, reflecting interest in immune-driven conditions.
- Asthma
- Chronic obstructive pulmonary disease
- Chronic rhinosinusitis with nasal polyps
- Hidradenitis suppurativa
- Crohn’s disease
Neurologic and cardiovascular areas include multiple sclerosis, epilepsy, migraine, trigeminal neuralgia, heart failure, and atherosclerotic cardiovascular disease.
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