Sergio H.
- Country
- Spain
- Department
- Oncology
Research Overview
Data & Insights
Has run more than one trial at 0 of 23 partner sites.
Specializations
Hematologic Malignancies
The investigator focuses on novel therapeutic strategies for multiple myeloma, including targeted antibodies and combination regimens aimed at improving depth of response.
- Antibody‑drug conjugates
- Immunomodulatory drug combinations
- Minimal residual disease assessment
Research includes evaluating efficacy and safety in patients undergoing autologous stem cell transplantation.
Solid Tumor Oncology
Active investigation of treatment options for early‑stage HER2‑negative breast cancer, castration‑resistant prostate cancer, and radioactive‑iodine refractory differentiated thyroid cancer emphasizes precision medicine and neoadjuvant approaches.
- Targeted HER3 inhibitors
- Second‑generation anti‑androgens with stereotactic radiotherapy
- Tyrosine‑kinase inhibitor biomarkers
Efforts aim to reduce recurrence risk and enhance long‑term survival across these tumor types.
Cardiovascular & Thrombotic Disorders
Research addresses prevention and management of acute vascular events, notably ischemic stroke after non‑cardioembolic episodes and intermediate‑risk pulmonary embolism, through anticoagulant and supportive interventions.
- Factor XIa inhibition
- Oxygen therapy protocols
- Risk stratification tools
Clinical outcomes such as stroke recurrence and pulmonary hemodynamics are central endpoints.
Immunology & Allergic Diseases
The investigator explores immune‑modulating treatments for allergic rhinoconjunctivitis and chronic inducible urticaria, including allergen immunotherapy and novel kinase inhibitors.
- Grass and olive pollen immunotherapy
- Remibrutinib efficacy in refractory urticaria
- Symptom‑medication composite scoring
Studies aim to achieve sustained symptom control and reduced medication reliance.
Women’s Health & Obstetrics
Focused efforts on conditions affecting women include preeclampsia prevention and management of stress urinary incontinence in post‑menopausal patients.
- Aspirin timing optimization
- Mesenchymal stem cell therapy for incontinence
- Maternal‑fetal outcome monitoring
Trials assess safety, efficacy, and quality‑of‑life improvements.
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