Sean C.
- Country
- Ireland
- Department
- Department of Radiation Oncology
Research Overview
Data & Insights
Has run more than one trial at 0 of 7 partner sites.
Specializations
Radiation Oncology & Solid Tumors
Focuses on the application of radiation therapy for a broad spectrum of solid malignancies.
- Breast Cancer (including HER2‑positive and triple‑negative subtypes)
- Non‑Small Cell Lung Cancer (early and metastatic stages)
- Ovarian and Fallopian Tube Cancers (platinum‑resistant and advanced)
- Prostate Cancer (high‑risk localized and metastatic castration‑resistant)
- Head and Neck Squamous Cell Carcinoma
These efforts aim to integrate advanced radiotherapeutic techniques with systemic therapies.
Hematologic Malignancies
Addresses malignant disorders of the blood and bone marrow with targeted therapeutic strategies.
- Acute Lymphoblastic Leukaemia
- Acute Myeloid Leukaemia (including IDH1‑mutant disease)
- Chronic Lymphocytic Leukaemia
- Mantle Cell Lymphoma
- Multiple Myeloma (newly diagnosed and relapsed/refractory)
- Myelodysplastic Syndromes
- Polycythemia Vera (JAK2V617F‑positive)
- Myelofibrosis
The program emphasizes innovative combinations of radiation, immunotherapy, and targeted agents.
Autoimmune & Renal Disorders
Targets immune‑mediated diseases affecting systemic and renal function.
- Systemic Lupus Erythematosus
- IgA Nephropathy
- Anti‑GBM Antibody Disease (Goodpasture syndrome)
- Primary Membranous Nephropathy
- Polymyalgia Rheumatica
- Eosinophilic Asthma
Research seeks disease‑modifying approaches to preserve organ function.
Infectious & Respiratory Diseases
Focuses on acute and chronic infections as well as respiratory conditions with high morbidity.
- COVID‑19 (SARS‑CoV‑2 infection)
- Monkeypox (mpox)
- Chronic Obstructive Pulmonary Disease
- Cystic Fibrosis
- Severe Asthma (eosinophilic phenotype)
Efforts aim to improve outcomes through novel antiviral and anti‑inflammatory strategies.
Rare Genetic & Metabolic Conditions
Investigates uncommon hereditary disorders that impact cancer biology and systemic health.
- CDKL5 Deficiency Disorder
- Hereditary Hemochromatosis (homeostatic iron regulator gene‑related)
- FGFR2b‑Overexpressing Gastric Cancer
- IDH1‑Mutant Acute Myeloid Leukaemia
- JAK2V617F‑Positive Polycythemia Vera
These studies explore precision‑medicine approaches tailored to molecular abnormalities.
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