Sashka Z.
- Country
- Bulgaria
- Department
- n/a
Research Overview
- A Phase 2b, Multi-center, Randomized, Double-blind, Placebo controlled Study of IMVT-1402 Treatment in Adult Participants with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
- A Phase 3, Randomized, Double-Blinded, Double-Dummy Study Evaluating the Efficacy and Safety of Intravenous Empasiprubart Versus Intravenous Immunoglobulin in Adults With Chronic Inflammatory Demyelinating Polyneuropathy
Data & Insights
Has run more than one trial at 20 of 92 partner sites.
Specializations
Autoimmune and Inflammatory Diseases
Sashka Zhelyazkova is involved in clinical research on rheumatoid arthritis, systemic lupus erythematosus, lupus nephritis, Sjögren’s syndrome, systemic sclerosis, and idiopathic inflammatory myopathies, with additional interest in broader immune-mediated disorders.
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Sjögren’s syndrome
- Systemic sclerosis
Her clinical portfolio also includes conditions such as psoriatic arthritis, polymyositis, and dermatomyositis, reflecting sustained involvement in therapies for complex autoimmune disease.
Respiratory and Allergic Disorders
Her research activity includes asthma, chronic obstructive pulmonary disease, bronchiectasis, idiopathic pulmonary fibrosis, and allergic rhinitis, with a clear therapeutic focus on airway inflammation and respiratory symptom control.
- Asthma
- Chronic obstructive pulmonary disease
- Idiopathic pulmonary fibrosis
- Allergic rhinitis
She is also engaged in studies for house dust mite allergy, supporting research in allergic airway disease and related immunologic treatment strategies.
Gastroenterology and Inflammatory Bowel Disease
Her clinical trial involvement covers ulcerative colitis, Crohn’s disease, and broader inflammatory bowel disease, indicating a strong interest in therapies for chronic intestinal inflammation.
- Ulcerative colitis
- Crohn’s disease
- Inflammatory bowel disease
- Moderately to severely active colitis
Her research landscape also includes treatment development for persistent gastrointestinal immune dysregulation, with attention to disease activity and symptom burden.
Neurology and Neuroimmunology
Sashka Zhelyazkova is active in studies of multiple sclerosis, relapsing forms of multiple sclerosis, progressive multiple sclerosis, chronic inflammatory demyelinating polyneuropathy, and upper limb spasticity after stroke or traumatic brain injury.
- Multiple sclerosis
- Chronic inflammatory demyelinating polyneuropathy
- Relapsing forms of multiple sclerosis
- Post-stroke spasticity
Her research also includes migraine and other nervous system diseases, extending her therapeutic interest across inflammatory and symptomatic neurologic conditions.
Cardiometabolic and Vascular Medicine
Her trial involvement spans atherosclerotic cardiovascular disease, atrial fibrillation, heart failure, hypertension, hyperlipidemia, hypertriglyceridemia, and obesity, reflecting a broad cardiometabolic research profile.
- Atherosclerotic cardiovascular disease
- Heart failure
- Hypertension
- Hypertriglyceridemia
She is also involved in research on high cardiovascular risk and resistant hypertension, supporting clinical innovation in vascular risk reduction and long-term cardiometabolic care.
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