Sarunas R.
- Country
- Lithuania
- Department
- Paediatric Department
Research Overview
- Evaluation of Vibegron for Safety, Efficacy, and Pharmacokinetics in Pediatric Patients with Neurogenic Detrusor Overactivity on Clean Intermittent Catheterization
- Randomized Trial of Early Versus Late Withdrawal of Etanercept, Baricitinib, and Tocilizumab in Juvenile Idiopathic Arthritis Remission Using Imaging and Multi-Omics
Data & Insights
Has run more than one trial at 2 of 37 partner sites.
Specializations
Rheumatology and Autoimmune Disease
Clinical trial activity includes rheumatoid arthritis, juvenile idiopathic arthritis, systemic lupus erythematosus, idiopathic inflammatory myopathy, and systemic sclerosis, with attention to inflammatory control and immune-mediated disease management.
- Rheumatoid arthritis
- Juvenile idiopathic arthritis
- Systemic lupus erythematosus
- Idiopathic inflammatory myopathy
- Systemic sclerosis
Therapeutic interests also extend to psoriatic arthritis, lupus nephritis, and other immune system diseases, reflecting involvement in targeted immunomodulatory care.
Inflammatory Bowel Disease and Gastroenterology
Research involvement includes Crohn’s disease and ulcerative colitis, with a focus on chronic intestinal inflammation and maintenance of disease control.
- Crohn’s disease
- Ulcerative colitis
- Moderately to severely active inflammatory bowel disease
- Endoscopic response
- Long-term disease control
The portfolio also includes related gastrointestinal cancers and gastroesophageal junction adenocarcinoma, broadening the therapeutic scope within digestive system disorders.
Neurology and Neuroinflammation
Clinical studies cover multiple sclerosis in relapsing and progressive forms, together with other disorders affecting the nervous system and neuromuscular function.
- Relapsing multiple sclerosis
- Secondary progressive multiple sclerosis
- Neurogenic detrusor overactivity
- Multifocal motor neuropathy
- Nervous system diseases
Additional interest is seen in migraine and stroke-related prevention, linking neurological care with vascular risk reduction.
Cardiovascular, Thromboembolic, and Renal Disorders
Trial activity includes acute coronary syndrome, heart failure, atrial fibrillation, atherosclerotic cardiovascular disease, and prevention of stroke and venous thromboembolism.
- Acute ischemic stroke
- Heart failure with reduced ejection fraction
- Atrial fibrillation
- Venous thromboembolism
- Chronic kidney disease and proteinuria
Research also spans immunoglobulin A nephropathy, proteinuria, and transthyretin amyloidosis with cardiomyopathy, indicating involvement in cardio-renal and systemic disease domains.
Paediatric Endocrine and Respiratory Care
Within the Paediatric Department, research interests include children with short stature, classic congenital adrenal hyperplasia, and type 1 diabetes, alongside chronic respiratory and allergic conditions.
- Children with short stature
- Classic congenital adrenal hyperplasia
- Type 1 diabetes
- Asthma
- Allergic rhinitis and rhinoconjunctivitis
Further activity includes bronchiectasis, chronic obstructive pulmonary disease, and severe eosinophilic asthma, supporting a broad paediatric and airway-focused therapeutic profile.
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