Sarina M.
- Country
- Germany
- Department
- HNO Klinik
Research Overview
- Phase IIa Randomized, Double-Blind, Placebo-Controlled Study of ACOU085 for Prevention of Cisplatin-Induced Sensorineural Hearing Loss in Testicular Cancer Patients
- Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of Itepekimab in Adults with Inadequately-Controlled Chronic Rhinosinusitis with Nasal Polyps
Data & Insights
Has run more than one trial at 3 of 59 partner sites.
Specializations
Head and Neck Oncology
Clinical research activity in the HNO Klinik in Erlangen includes treatment areas for head and neck squamous cell carcinoma, locoregionally recurrent disease, and resectable advanced head and neck tumors, with interest in improving disease control and surgical-adjunct strategies.
- Head and neck squamous cell carcinoma
- Locoregionally recurrent head and neck cancer
- Resectable locally advanced head and neck malignancy
Research involvement also extends to nasopharyngeal carcinoma and broader neoplasms of the head and neck.
Breast Cancer and Solid Tumors
The investigator is involved in studies across breast cancer, particularly hormone receptor-positive, HER2-negative, HER2-positive, and triple negative breast cancer, alongside research in advanced solid tumors and metastatic disease.
- Early breast cancer
- Metastatic breast cancer
- Triple negative breast cancer
Additional therapeutic interest includes post-neoadjuvant treatment and biomarker-guided therapy in high-risk disease.
Autoimmune and Inflammatory Disease
Research activity covers a wide range of immune-mediated disorders, including atopic dermatitis, hidradenitis suppurativa, psoriasis, psoriatic arthritis, systemic lupus erythematosus, cutaneous lupus erythematosus, and systemic sclerosis.
- Atopic dermatitis
- Hidradenitis suppurativa
- Systemic lupus erythematosus
Therapeutic interest also includes Crohn’s disease, ulcerative colitis, primary sclerosing cholangitis, and rheumatoid arthritis.
Hematologic Malignancies and Cellular Therapies
The clinical portfolio includes acute lymphoblastic leukemia, acute myeloid leukemia, chronic myeloid leukemia, diffuse large B-cell lymphoma, high-grade B-cell lymphoma, and multiple myeloma, with a strong focus on advanced hematologic treatment options.
- Acute lymphoblastic leukemia
- Diffuse large B-cell lymphoma
- Multiple myeloma
Interest also extends to CAR-T cell therapy, gene-modified T cells, and stem cell transplantation.
Neurology, Nephrology, and Rare Disease
Research involvement spans multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, epilepsy, and status epilepticus, together with renal and rare immune conditions such as chronic kidney disease, IgA nephropathy, lupus nephritis, and anti-GBM antibody disease.
- Multiple sclerosis
- Neurodegenerative disease
- Immune-mediated kidney disease
Additional areas include stroke prevention, dementia, and selected rare pediatric and genetic disorders.
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