Sara T.
- Country
- Italy
- Department
- Interventional Pulmonology Unit
Research Overview
- Evaluation of ARO-MMP7 Inhalation Solution in Idiopathic Pulmonary Fibrosis: A Phase 1/2a Clinical Trial in Healthy Subjects and Patients
- Phase 2 Randomized, Double-Blind, Placebo-Controlled Study on the Efficacy and Safety of MBS2320 in Idiopathic Pulmonary Fibrosis Patients
- Efficacy and Safety Evaluation of Bexotegrast in Idiopathic Pulmonary Fibrosis: A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study
Data & Insights
Has run more than one trial at 102 of 216 partner sites.
Specializations
Thoracic Oncology
Clinical research in non-small cell lung cancer, small cell lung cancer, and other thoracic malignancies, with interest in both resectable and metastatic disease, as well as biomarker-defined subtypes such as EGFR-mutated, ALK-positive, and KRAS G12C-mutant tumors.
- Non-small cell lung cancer
- Small cell lung cancer
- Head and neck squamous cell carcinoma
- Pulmonary large-cell neuroendocrine carcinoma
Therapeutic activity also extends to lung fibrosis and interstitial lung disease in the setting of progressive respiratory disorders.
Breast and Gynecologic Oncology
The investigator is involved in studies of breast cancer across early, locally advanced, and metastatic settings, including hormone receptor-positive, HER2-negative, and triple-negative disease, alongside ovarian cancer, endometrial cancer, and cervical cancer.
- Breast cancer
- Triple-negative breast cancer
- Ovarian cancer
- Endometrial cancer
Research interests include endocrine therapy, PARP inhibitor-based strategies, and treatment approaches for platinum-resistant and HRD-positive gynecologic malignancies.
Hematology and Hematologic Malignancies
Her clinical trial portfolio includes acute myeloid leukemia, myelodysplastic syndromes, multiple myeloma, chronic lymphocytic leukemia, and lymphoma, with additional involvement in myeloproliferative neoplasms such as myelofibrosis, essential thrombocythemia, and polycythemia vera.
- Acute myeloid leukemia
- Myelodysplastic syndromes
- Multiple myeloma
- Myelofibrosis
She also contributes to research on anemia, hemophilia, and other blood and lymphatic disorders.
Autoimmune, Inflammatory, and Respiratory Disease
Her research spans rheumatoid arthritis, psoriatic arthritis, systemic sclerosis, systemic lupus erythematosus, Crohn’s disease, and ulcerative colitis, reflecting a strong focus on immune-mediated conditions.
- Rheumatoid arthritis
- Crohn’s disease
- Ulcerative colitis
- Systemic sclerosis
Additional interest is seen in asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, pulmonary sarcoidosis, and eosinophilic inflammatory disorders.
Cardiovascular, Renal, and Metabolic Medicine
The investigator is active in trials addressing atherosclerotic cardiovascular disease, atrial fibrillation, myocardial infarction, stroke prevention, and cardiomyopathy, including transthyretin amyloid cardiomyopathy and hypertrophic cardiomyopathy.
- Atrial fibrillation
- Transthyretin amyloid cardiomyopathy
- Chronic kidney disease
- IgA nephropathy
Her portfolio also includes chronic kidney disease, IgA nephropathy, diabetic retinopathy, diabetic macular edema, and metabolic dysfunction-associated steatotic liver disease.
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