Salvatore P.
- Country
- Italy
- Department
- Dep. Of Internal Medicine and Specialistic
Research Overview
- N1T-MC-MALO: A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes (SYNERGY-Outcomes); N1T-MC-TZ01 Tirzepatide in participants with high-risk MASLD; N1T-MC-RT01 Retatrutide in participants with high-risk MASLD
- Evaluation of AZD2693 Sodium Efficacy, Safety, and Tolerability in Non-Cirrhotic NASH with Fibrosis and PNPLA3 rs738409 148M Allele Carriers
- Evaluation of Semaglutide in Patients with Non-Cirrhotic Non-Alcoholic Steatohepatitis and Fibrosis Stages 2 or 3: A Randomized, Placebo-Controlled Trial
Data & Insights
Has run more than one trial at 120 of 244 partner sites.
Specializations
Liver Disease Management
The investigator specializes in treating non-alcoholic steatohepatitis (NASH) and its various manifestations, with particular attention to patients with different stages of liver fibrosis.
- Advanced liver fibrosis treatment
- NASH resolution strategies
- Cirrhosis management
Their expertise extends to addressing metabolic dysfunction-associated steatohepatitis (MASH) in patients with compensated cirrhosis.
Therapeutic Innovation
The investigator focuses on evaluating novel therapeutic approaches for liver diseases, including genetic marker-specific treatments and targeted interventions for specific patient populations.
- PNPLA3 genetic marker studies
- Innovative drug development
- Long-term therapeutic outcomes
Their work encompasses both oral and injectable therapeutic modalities for liver disease treatment.
Clinical Outcomes
The investigator's work centers on measuring and improving histological improvements in liver condition and evaluating long-term clinical outcomes.
- Liver biopsy assessment
- Fibrosis regression analysis
- Disease progression monitoring
They specialize in evaluating therapeutic efficacy through comprehensive histological and clinical endpoints.
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