Ruxandra S.
- Country
- Romania
- Department
- AEM in colab. with Arensia Clinics, 3rd floor, Wrds 1,2,3,4,5,6,7,Tudor Stefan Str,Bucharest
Research Overview
Data & Insights
Has run more than one trial at 2 of 30 partner sites.
Specializations
Ophthalmology and retinal disease
Ruxandra Simionescu is involved in clinical research focused on geographic atrophy and age-related macular degeneration, with interest in therapies aimed at preserving retinal structure and function in degenerative eye disease.
- Geographic atrophy
- Age-related macular degeneration
- Intravitreal therapy
Her work in ophthalmology extends to treatment development for progressive macular conditions that contribute to central vision loss.
Autoimmune and inflammatory disease
Her research landscape includes multiple immune-mediated disorders, with therapeutic interest in systemic lupus erythematosus, rheumatoid arthritis, Sjögren’s syndrome, and psoriasis.
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Sjögren’s syndrome
- Chronic plaque psoriasis
She is also connected with studies in other immune-driven conditions, including bullous pemphigoid, dermatomyositis, and Behçet’s syndrome.
Neurology and demyelinating disease
Clinical activity in multiple sclerosis reflects involvement in therapies for relapsing forms of central nervous system inflammation, including work relevant to relapsing-remitting multiple sclerosis.
- Multiple sclerosis
- Relapsing-remitting multiple sclerosis
- Neuroinflammatory disease
This area includes investigational interest in treatments designed to address disease activity and immune modulation in chronic neurologic autoimmunity.
Gastroenterology and intestinal inflammation
Her trial involvement also covers ulcerative colitis and broader inflammatory bowel disease, with attention to therapies for persistent mucosal inflammation and relapsing gastrointestinal disease.
- Ulcerative colitis
- Inflammatory bowel disease
- Chronic intestinal inflammation
These studies align with therapeutic development in immune-mediated disorders affecting the colon and rectum.
Metabolic, cardiovascular, and hematologic complications
Her research interests extend to overweight and obesity, atherosclerotic cardiovascular disease, chronic kidney disease, and venous thromboembolism, showing engagement across cardiometabolic and thrombotic risk states.
- Overweight and obesity
- Atherosclerotic cardiovascular disease
- Chronic kidney disease
- Venous thromboembolism
Her portfolio also includes immune thrombocytopenia, antiphospholipid syndrome, and selected B-cell malignancies, reflecting a broad therapeutic scope in systemic disease.
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