Ruta T.
- Country
- Denmark
- Department
- Department of Paediatrics and Adolescent Medicine
Research Overview
- Revumenib in Combination with Fludarabine and Cytarabine for Pediatric Refractory or Relapsed KMT2A-r, NUP98-r, or NPM1-mut Acute Myeloid Leukemia
- Safety and Efficacy of Asciminib, Blinatumomab, and Combination Therapy in Pediatric and Young Adult Patients with Relapsed/Refractory BCR::ABL1+ or Ph-like ALL
- International proof of concept therapeutic Stratification trial of Molecular Anomalies in Relapsed or Refractory HEMatological malignancies in children - Sub-protocol D
Data & Insights
Has run more than one trial at 42 of 65 partner sites.
Specializations
Pediatric Hematologic Malignancies
The investigator specializes in treating various types of blood cancers in children, with particular focus on acute lymphoblastic leukemia and lymphoma variants. Their expertise extends to both B-cell and T-cell malignancies.
- Relapsed/Refractory Leukemia
- B-Cell Non-Hodgkin Lymphoma
- T-Cell Lymphoblastic Lymphoma
Their work includes evaluation of novel therapeutic combinations for treatment-resistant cases.
Rare Pediatric Conditions
The investigator conducts research in rare pediatric disorders, including Pyruvate Kinase Deficiency and ALK-positive tumors. Their work addresses both hematological and solid tumor manifestations of these conditions.
- Transfusion-Dependent PK Deficiency
- Inflammatory Myofibroblastic Tumors
- Anaplastic Large Cell Lymphoma
Their research focuses on developing targeted therapies for these challenging conditions.
Novel Therapeutic Approaches
The investigator explores innovative treatment strategies using targeted molecular therapies and combination treatments. Their research encompasses both monotherapy and combination approaches in pediatric oncology.
- Signal Pathway Inhibitors
- Chemoimmunotherapy Combinations
- Molecular-Based Treatment Strategies
Their work aims to improve outcomes in treatment-resistant pediatric cancers.
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