Roser S. I. L.
- Country
- Spain
- Department
- Internal Medicine
Research Overview
- Efficacy and Safety of Depemokimab vs. Mepolizumab in Adults with Relapsing/Refractory Eosinophilic Granulomatosis with Polyangiitis (EGPA)
- Evaluation of Hydroxychloroquine with Leflunomide and Hydroxychloroquine with Mycophenolate Mofetil in Primary Sjögren's Syndrome: A Stratified Interventional Trial
- Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of Nipocalimab in Adults with Moderate to Severe Sjögren's Disease
Data & Insights
Has run more than one trial at 19 of 132 partner sites.
Specializations
Oncology – Advanced Solid Tumors
The investigator leads studies on advanced solid tumors across a wide anatomical spectrum, emphasizing molecularly defined sub‑groups.
- Estrogen Receptor‑Positive HER2‑Negative Breast Cancer
- Non‑Small Cell Lung Cancer with KRAS G12C mutation
- Metastatic Colorectal Cancer
- Advanced Gastric and Gastroesophageal Junction Adenocarcinoma
- Renal Cell Carcinoma with MET alteration
All trials are conducted at Hospital Vall d’Hebron, integrating precision‑medicine approaches.
Hematologic Malignancies
Research activity includes high‑risk myeloid and lymphoid neoplasms, targeting disease‑specific genetic drivers.
- Acute Myeloid Leukemia
- Myelodysplastic Syndrome
- Chronic Lymphocytic Leukemia
- Mantle Cell Lymphoma
- Multiple Myeloma
Therapeutic strategies explore novel agents and combination regimens within the internal medicine department.
Autoimmune & Inflammatory Disorders
Focused investigations address systemic autoimmunity and organ‑specific inflammatory conditions.
- Systemic Lupus Erythematosus
- Cutaneous Lupus Erythematosus
- Psoriatic Arthritis
- Rheumatoid Arthritis
- Myasthenia Gravis
Clinical protocols evaluate targeted immunomodulation and biomarker‑guided therapy.
Respiratory & Infectious Diseases
Activities span chronic pulmonary disorders and challenging infectious entities.
- Obstructive Sleep Apnea in obesity
- Nontuberculous Mycobacterial lung infection
- COVID‑19
- Acute bacterial skin and skin‑structure infections
- Bronchiectasis
Trials prioritize novel antimicrobial agents and airway‑targeted therapeutics.
Cardiovascular & Metabolic Conditions
Research encompasses atherosclerotic disease, heart failure, and metabolic risk factors.
- Atherosclerotic Cardiovascular Disease
- Heart Failure with reduced ejection fraction
- Type 2 Diabetes Mellitus
- Obesity
- Hypertension
Investigations assess cardiovascular outcomes and metabolic control in high‑risk cohorts.
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