Rosalia M. P.
- Country
- Portugal
- Department
- Reumatology
Research Overview
- Evaluation of Dazodalibep Efficacy and Safety in Patients with Moderate-to-Severe Sjögren’s Syndrome: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study
- Efficacy and Safety Evaluation of Dazodalibep in Patients with Moderate-to-Severe Systemic Sjögren’s Syndrome: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study
- Efficacy and Safety of Targeted Therapeutic Strategies in Adults with Rheumatoid Arthritis: A Randomized, Double‑Blind, Placebo‑Controlled Study
Data & Insights
Has run more than one trial at 123 of 317 partner sites.
Specializations
Rheumatology and systemic autoimmune disease
Research activity includes rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, juvenile idiopathic arthritis, systemic sclerosis, Sjögren’s disease, vasculitis, and myositis, with additional involvement in Behçet’s disease, antiphospholipid syndrome, and myasthenia gravis.
- Inflammatory rheumatic diseases
- Connective tissue diseases
- Autoimmune cytopenias
- Cutaneous lupus
- Interstitial lung disease associated with autoimmune disorders
The portfolio also extends to lupus nephritis, renal involvement, and refractory inflammatory phenotypes that intersect with broader immune-mediated organ disease.
Hematologic malignancies and cellular therapy
Clinical research spans multiple myeloma, acute myeloid leukemia, myelodysplastic syndromes, chronic lymphocytic leukemia, follicular lymphoma, diffuse large B-cell lymphoma, mantle cell lymphoma, and Waldenström macroglobulinemia.
- B-cell lymphomas
- Plasma cell disorders
- Myeloid neoplasms
- Graft-versus-host disease
- CAR T-cell therapy
Interest also includes relapsed and refractory hematologic disease, post-transplant complications, and immune-mediated toxicity management in advanced blood cancers.
Solid tumors and precision oncology
The oncology portfolio covers breast cancer, non-small cell lung cancer, small cell lung cancer, renal cell carcinoma, urothelial carcinoma, ovarian cancer, endometrial cancer, colorectal cancer, gastric cancer, and head and neck squamous cell carcinoma.
- Targeted therapy
- Immuno-oncology
- HER2-positive and HR-positive breast cancer
- Biomarker-driven solid tumors
- Metastatic disease
Additional activity includes molecularly selected cancers, advanced solid tumors, and treatment strategies for brain metastases and high-risk recurrent disease.
Cardiometabolic, renal, and hepatic disease
Research involvement includes atherosclerotic cardiovascular disease, heart failure, atrial fibrillation, myocardial infarction, chronic kidney disease, IgA nephropathy, proteinuric glomerular disease, liver cirrhosis, portal hypertension, and metabolic dysfunction-associated steatohepatitis.
- Cardiovascular risk reduction
- Renal protection
- Liver disease
- Thromboembolic disease
- Metabolic disorders
The portfolio also touches obesity, dyslipidemia, type 2 diabetes, and other chronic conditions linked to long-term organ damage.
Respiratory, neurologic, and inflammatory disorders
Additional studies address asthma, chronic obstructive pulmonary disease, obstructive sleep apnea, interstitial lung disease, idiopathic pulmonary fibrosis, Parkinson’s disease, multiple sclerosis, migraine, and Alzheimer’s disease.
- Airway inflammation
- Fibrotic lung disease
- Neurodegenerative disease
- Demyelinating disease
- Chronic inflammatory disorders
Her research landscape also includes atopic dermatitis, psoriasis, hidradenitis suppurativa, and other immune-mediated conditions affecting skin, airway, and nervous system pathways.
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