Rosa T.
- Country
- Italy
- Department
- Dipartimento Corp-S di ricerca e assistenziale dei percorsi oncologici del distretto urogenitale
Research Overview
- A Phase 2 Multi-Cohort, Open-Label, Multi-Center Clinical Study Evaluating the Efficacy and Safety of Disitamab Vedotin (RC48-ADC) Alone and in Combination with Pembrolizumab in Subjects with Locally Advanced Unresectable or Metastatic Urothelial Carcinoma That Expresses HER2
- Phase 2 Open‑Label Single‑Arm Study of Enfortumab Vedotin Plus Pembrolizumab for Bladder Preservation in Patients with Muscle‑Invasive Bladder Cancer
- A Phase 3, Randomized, Double-blind Study to Evaluate Perioperative Pembrolizumab (MK-3475) + Neoadjuvant Chemotherapy versus Perioperative Placebo + Neoadjuvant Chemotherapy in Cisplatin-eligible Participants with Muscle-invasive Bladder Cancer (KEYNOTE-866)
Data & Insights
Has run more than one trial at 185 of 347 partner sites.
Specializations
Advanced Urothelial Cancer
Specializes in investigating novel therapeutic approaches for locally advanced and metastatic urothelial carcinoma, with particular emphasis on immunotherapy combinations and targeted treatments.
- First-line treatment strategies
- HER2-targeted therapies
- Immunotherapy combinations
Explores various treatment pathways including anti-PD-1/PD-L1 therapies and antibody-drug conjugates.
Muscle-Invasive Bladder Cancer
Focuses on developing perioperative treatment approaches for muscle-invasive bladder cancer, incorporating both immunotherapy and chemotherapy protocols.
- Neoadjuvant therapeutic strategies
- Perioperative immunotherapy
- Radical cystectomy outcomes
Investigates treatment options for both cisplatin-eligible and ineligible patients.
Non-Muscle Invasive Bladder Cancer
Conducts research on innovative intravesical treatments for non-muscle invasive bladder cancer, particularly focusing on BCG-unresponsive disease.
- Novel intravesical therapies
- Treatment-resistant disease
- Carcinoma in situ management
Evaluates experimental therapeutic approaches for high-risk bladder cancer patients.
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