Rosa G.
- Country
- Italy
- Department
- Ophthalmology Clinical Operating Unit
Research Overview
Data & Insights
Has run more than one trial at 0 of 33 partner sites.
Specializations
Ophthalmology – Glaucoma Therapeutics
Focused on preserving visual function in open angle glaucoma. The work emphasizes neuroprotective strategies.
- Citicoline eye‑drop formulation
- Visual field preservation outcomes
- Adjunctive therapy to intra‑ocular pressure control
Research integrates ocular pharmacology with clinical practice guidelines.
Cardiovascular & Heart Failure Inflammation
Investigates anti‑inflammatory approaches in heart failure with preserved ejection fraction. A parallel focus is on heart failure with mildly reduced ejection fraction.
- Ziltivekimab monthly subcutaneous administration
- MACE risk reduction
- Integration with standard heart‑failure care
Efforts aim to lower cardiovascular mortality linked to systemic inflammation.
Cerebrovascular Stroke Prevention
Evaluates antithrombotic agents to prevent recurrent ischemic stroke. The program also addresses high‑risk transient ischemic attack.
- Milvexian factor XI inhibition
- Early mortality reduction within seven days
- Placebo‑controlled efficacy assessment
Therapeutic goals include lowering recurrence and improving acute outcomes.
Hematologic Oncology – B‑Cell Lymphomas
Explores novel immunotherapies for aggressive diffuse large B‑cell lymphoma. Additional interest lies in indolent follicular lymphoma and marginal zone lymphoma.
- Epcoritamab bispecific antibody
- Combination with lenalidomide
- Rituximab‑based regimen enhancement
Research targets improved response rates in relapsed or refractory disease.
Renal Disease & Systemic Inflammation
Targets cardiovascular risk in patients with chronic kidney disease. The approach emphasizes modulation of systemic inflammation.
- Ziltivekimab anti‑inflammatory therapy
- Biomarker‑driven outcome measures
- Combination with standard of care
Objective is to reduce major adverse cardiovascular events in this high‑risk population.
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