Ron P.
- Country
- The Netherlands
- Department
- Cardiology Department
Research Overview
- Evaluation of Aspirin Omission on Bleeding and Ischemic Outcomes in Non-ST-Segment Elevation Acute Coronary Syndrome Patients
- Phase 3, Multicenter, Placebo‑Controlled Study of Intranasal Etripamil for Rapid Ventricular Rate Control in Atrial Fibrillation (ReVeRA‑301)
- Phase 3 Randomized Study Comparing Asundexian and Apixaban for Stroke Prevention in Atrial Fibrillation Patients at Risk
Data & Insights
Has run more than one trial at 320 of 978 partner sites.
Specializations
Cardiovascular disease and thrombosis
Clinical activity centers on cardiology with a strong focus on atherosclerotic cardiovascular disease, acute myocardial infarction, heart failure, atrial fibrillation, stroke, and peripheral arterial disease. The research portfolio also includes prevention of recurrent vascular events, lipid-related risk reduction, and management of venous thromboembolism.
- Acute coronary syndromes
- Stroke prevention
- Lipid disorders
- Heart failure
- Antithrombotic therapy
Work in this area also extends to cardiometabolic risk, including obesity, hypertriglyceridemia, and elevated lipoprotein(a), with interest in therapies aimed at reducing vascular events.
Hematologic malignancies
Research involvement covers a broad spectrum of blood cancers, with emphasis on acute myeloid leukemia, chronic lymphocytic leukemia, multiple myeloma, and lymphoma. The portfolio also includes myelodysplastic syndrome and related relapsed or treatment-naive hematologic conditions.
- Acute myeloid leukemia
- Chronic lymphocytic leukemia
- Multiple myeloma
- Non-Hodgkin lymphoma
- Myelodysplastic syndrome
Interest in this domain includes targeted and immune-based approaches for relapsed/refractory disease and treatment strategies for patients with limited options.
Solid tumors and gastrointestinal oncology
The oncology profile includes extensive work in non-small cell lung cancer, small cell lung cancer, bladder cancer, urothelial carcinoma, breast cancer, gastric cancer, rectal cancer, and prostate cancer. Gastroesophageal, renal, and neuroendocrine tumors are also represented.
- Non-small cell lung cancer
- Bladder and urothelial cancer
- Breast cancer
- Gastroesophageal cancer
- Neuroendocrine tumors
Therapeutic interest spans perioperative, metastatic, and biomarker-defined settings, with attention to immunotherapy, targeted therapy, and antibody-drug conjugates.
Respiratory, infectious, and inflammatory disease
Additional research areas include chronic obstructive pulmonary disease, severe asthma, pneumonia, influenza, and lower respiratory tract infection. The investigator is also involved in studies of inflammatory bowel disease, Crohn's disease, ulcerative colitis, and other immune-mediated disorders.
- Chronic obstructive pulmonary disease
- Severe asthma
- Respiratory infection
- Inflammatory bowel disease
- Autoimmune inflammation
This area also includes interest in acute pancreatitis, sepsis-related infection, and other conditions where inflammation and organ dysfunction shape treatment needs.
Neurology, endocrine, and metabolic disorders
Clinical trial involvement further extends to multiple sclerosis, ischemic stroke, intracerebral hemorrhage, insomnia, and depression. Endocrine and metabolic interests include type 2 diabetes, obesity, thyroid disorders, polycystic ovary syndrome, and infertility.
- Multiple sclerosis
- Stroke
- Type 2 diabetes
- Obesity
- Thyroid and reproductive disorders
The portfolio reflects engagement with therapies for chronic neurological symptoms, cardiometabolic risk, and selected reproductive endocrine conditions.
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