Roisin C.
- Country
- Ireland
- Department
- Cardiology
Research Overview
Data & Insights
Has run more than one trial at 0 of 310 partner sites.
Specializations
Prostate Cancer Therapeutics
Focused on advanced and high‑risk Prostate Cancer strategies, including hormonal manipulation and targeted radiation approaches.
- Androgen Deprivation Therapy
- Darolutamide
- Metastatic Castration‑Resistant Prostate Cancer
- Functional Imaging‑Guided Oligometastatic Treatment
Efforts aim to improve survival outcomes while preserving quality of life for men with aggressive disease.
Breast Cancer Hormone‑Responsive Treatments
Engaged in clinical studies of endocrine‑based regimens for Hormone Receptor‑Positive, HER2‑Negative Breast Cancer, spanning early and high‑risk settings.
- CDK4/6 Inhibitors
- Selective Estrogen Receptor Degraders
- Oncotype DX Recurrence Score
- Adjuvant Chemotherapy Decision‑Making
Research seeks to refine adjuvant therapy selection and reduce overtreatment.
Lung Cancer Targeted and Immunotherapy
Investigates novel combinations for Non‑Small Cell Lung Cancer, with emphasis on molecular subtypes and immune modulation.
- KRAS G12C Inhibition
- Pembrolizumab‑Based Immunotherapy
- Axitinib Combination Strategies
- c‑Met Positive Tumors
Goal is to extend progression‑free intervals and enhance overall survival.
Cardiovascular Disease and Heart Failure Management
Contributes to trials addressing Heart Failure with Preserved Ejection Fraction and systemic inflammation, as well as lipid‑related risk reduction.
- Ziltivekimab
- Lipoprotein(a) Lowering Therapies
- Inflammatory Biomarker‑Targeted Interventions
- Cardiovascular Event Prevention
Studies aim to lower cardiovascular mortality and hospitalization rates.
Renal Cell Carcinoma and Emerging Oncology
Participates in investigations of immune‑checkpoint and VEGF pathway blockade for Renal Cell Carcinoma and related malignancies.
- Pembrolizumab
- Axitinib
- Combination Immunotherapy Regimens
- Biomarker‑Driven Patient Selection
Efforts focus on optimizing therapeutic sequencing and durability of response.
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