Roberto M.
- Country
- France
- Department
- Diabetology
Research Overview
- 48‑Week Verapamil Hydrochloride to Preserve Beta‑Cell Function in Ages 7–45 With Stage 1 or 2 Type 1 Diabetes – Randomized Placebo‑Controlled Trial
- A 52-week randomized, double-blind, placebo-controlled, multi-center Phase 2b study with a 52-week blinded extension and an optional open-label extension—assessing the safety and efficacy of frexalimab, a CD40L-antagonist monoclonal antibody, for the preservation of pancreatic β-cell function in adults and adolescents with newly diagnosed type 1 diabetes on insulin therapy
- Long-term Verapamil Hydrochloride Therapy in Type 1 Diabetes Mellitus: A Multi-Center Study on Beta-Cell Function Preservation
Data & Insights
Has run more than one trial at 16 of 77 partner sites.
Specializations
Diabetes Research Focus
This investigator specializes in Type 1 diabetes mellitus research, with particular emphasis on preserving endogenous insulin secretion and beta-cell function in newly diagnosed patients.
- Beta-cell preservation strategies
- Early-stage diabetes interventions
- Insulin secretion maintenance
Their work encompasses both adult and adolescent patient populations, exploring innovative therapeutic approaches for diabetes management.
Therapeutic Interventions
The investigator conducts research on various therapeutic agents including Verapamil SR and interleukin-2 treatments, focusing on their potential in diabetes management.
- Novel drug applications
- Long-term therapeutic effects
- Combination therapy approaches
Their research examines both immediate and extended treatment outcomes in diabetes care.
Clinical Assessment Methods
The investigator utilizes advanced clinical assessment techniques, including mixed-meal tolerance testing and C-peptide response evaluation.
- Metabolic response monitoring
- Endocrine function assessment
- Long-term outcome measurement
Their research implements comprehensive monitoring protocols to evaluate treatment effectiveness.
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