Roberta M.
- Country
- Italy
- Department
- Struttura Complessa di Ematologia Ospedale Oncologico Armando Businco, Via Edward Jenner, 1)
Research Overview
- An open-label, randomized phase III trial comparing local radiotherapy alone or combined with Obinutuzumab in early stage Follicular Lymphoma: the GAZEBO Trial from the Fondazione Italiana Linfomi
- Evaluation of Venetoclax and Obinutuzumab, with or without Zanubrutinib, in High-Risk Chronic Lymphocytic Leukemia in Young Patients
- A Phase IV, Multicenter, Open-Label, Randomized Study of Acalabrutinib Monotherapy Versus Investigator's Choice in Chronic Lymphocytic Leukemia with Cardiac Impairment
Data & Insights
Has run more than one trial at 76 of 221 partner sites.
Specializations
Hematologic Malignancies
Roberta Murru is involved in clinical research across a broad spectrum of blood cancers, with particular attention to acute leukemia, lymphoid neoplasms, and plasma cell disorders. The clinical landscape includes studies in acute myeloid leukemia, acute lymphoblastic leukemia, chronic lymphocytic leukemia, multiple myeloma, and mantle cell lymphoma, alongside other aggressive and indolent lymphoma subtypes.
- Acute leukemia
- Chronic lymphocytic leukemia
- Non-Hodgkin lymphoma
- Multiple myeloma
Her work also extends to stem cell transplantation-related settings and minimal residual disease-driven treatment strategies in hematologic oncology.
Pediatric and Adolescent Oncology
Her research portfolio includes multiple trials in childhood and adolescent cancers, with emphasis on pediatric leukemia, lymphoblastic lymphoma, neuroblastoma, medulloblastoma, ependymoma, and rhabdomyosarcoma. These studies reflect involvement in both newly diagnosed and relapsed disease across developmental age groups.
- Pediatric acute lymphoblastic leukemia
- High-risk neuroblastoma
- Medulloblastoma
- Rhabdomyosarcoma
She is also connected to research in pediatric central nervous system tumors and age-adapted treatment approaches for younger patients.
Gastroenterology and Immune-Mediated Disease
Roberta Murru’s clinical trial activity includes inflammatory bowel disease and immune-mediated renal disease, with studies in Crohn's disease, ulcerative colitis, and IgA nephropathy. Her involvement also covers broader immune system disorders and inflammatory conditions affecting organ function.
- Crohn's disease
- Ulcerative colitis
- IgA nephropathy
- Immune-mediated disease
These research areas highlight interest in targeted immunotherapy and organ-specific inflammatory disease management.
Head and Neck Cancer and Solid Tumors
Her portfolio includes trials in head and neck squamous cell carcinoma, as well as selected studies in other solid tumors such as medulloblastoma, neuroblastoma, and ependymoma. The head and neck oncology work spans recurrent, metastatic, and resected disease settings.
- Head and neck squamous cell carcinoma
- Metastatic solid tumors
- Resected malignancy
- Recurrent disease
Her clinical research in this field is linked to immuno-oncology and combination treatment strategies in difficult-to-treat tumor types.
Transplantation, Infection, and Supportive Care
Roberta Murru is also active in studies addressing hematopoietic stem cell transplantation-associated complications, cytomegalovirus infection, febrile neutropenia, and cardiac arrhythmia. Additional research includes stroke, electrical storm, major depressive disorder, and autism spectrum disorder in selected clinical settings.
- Hematopoietic stem cell transplantation
- Cytomegalovirus infection
- Febrile neutropenia
- Cardiac and neurologic supportive care
Her trial activity reflects engagement with supportive oncology, infection control, and complication management in complex hematology patients.
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