Rikke K. O.
- Country
- Denmark
- Department
- Department of Oncology
Research Overview
Data & Insights
Has run more than one trial at 0 of 4 partner sites.
Specializations
Solid Tumor Oncology
Investigates targeted and immunotherapeutic approaches for advanced breast cancer, non‑small cell lung cancer, and colorectal cancer.
- Therapies for HER2‑positive breast cancer
- Interventions targeting KRAS G12C in colorectal disease
- Checkpoint inhibition using PD‑L1 in lung carcinoma
- Combination regimens for metastatic pancreatic adenocarcinoma
Efforts emphasize biomarker‑guided patient selection across metastatic solid tumors.
Hematologic Malignancies
Focuses on novel agents for malignant blood disorders such as multiple myeloma and chronic lymphocytic leukemia.
- Anti‑CD38 strategies in multiple myeloma
- BCL‑2 inhibition for CLL
- Bispecific antibodies targeting B‑cell lymphoma
- Maintenance therapies post‑autologous stem cell transplant
Research integrates molecular profiling to refine therapeutic sequencing.
Respiratory and Pulmonary Diseases
Dedicated to improving outcomes in chronic airway conditions including asthma and chronic obstructive pulmonary disease.
- Biologic modulation of type‑2 inflammation in severe asthma
- Eosinophil‑targeted treatment for exacerbation‑prone COPD
- Anti‑fibrotic approaches for pulmonary sarcoidosis
- Antibiotic stewardship in non‑cystic fibrosis bronchiectasis
Clinical programs assess long‑term lung function preservation.
Autoimmune and Inflammatory Disorders
Explores disease‑modifying therapies for systemic immune‑mediated conditions such as psoriatic arthritis and polymyalgia rheumatica.
- IL‑17 inhibition in psoriatic arthritis
- Glucocorticoid‑sparing regimens for polymyalgia rheumatica
- Targeted treatment of sarcoidosis with corticosteroid reduction
- Management of Sjögren’s syndrome manifestations
Trials prioritize patient‑reported outcomes and steroid minimization.
Metabolic, Cardiovascular and Renal Health
Addresses comorbidities intersecting oncology, focusing on type 2 diabetes, cardiovascular disease, and chronic kidney disease.
- Cardiovascular risk reduction in diabetic cohorts
- Imaging‑guided strategies for subclinical atherosclerosis
- Renal protective approaches for patients receiving nephrotoxic oncology therapies
- Integrated care pathways for obesity‑related metabolic syndrome
Cross‑disciplinary studies aim to mitigate treatment‑related systemic toxicity.
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