Richard E.
- Country
- Germany
- Department
- Klinik für An#sthesie und Schmerzmedizin
Research Overview
- Effect of Sodium Hydrogen Carbonate on Major Adverse Kidney Events in Critically Ill Patients with Metabolic Acidosis and Acute Kidney Injury
- Phase 3 Trial of VMX-C001 Versus Usual Care in Patients on Factor Xa DOACs Requiring Urgent High-Bleeding-Risk Surgery or Invasive Procedures
- A Randomized Controlled Trial of Angiotensin II Versus Noradrenaline for Prevention of Cardiac Surgery-Associated Acute Kidney Injury
Data & Insights
Has run more than one trial at 27 of 122 partner sites.
Specializations
Paediatric haematology and leukaemia
Clinical activity includes treatment research in acute lymphoblastic leukaemia, acute myeloid leukaemia, lymphoblastic lymphoma, and related high-risk childhood haematologic malignancies, with interest in treatment optimisation, relapse management, and risk-adapted therapy.
- Philadelphia chromosome-positive ALL
- Relapsed and refractory leukaemia
- Infant ALL
- Mature B-cell lymphoma
The therapeutic focus also extends to biomarker-informed approaches and immunotherapy-based strategies in aggressive paediatric blood cancers.
Paediatric solid tumours and neuro-oncology
Research interests cover a broad range of childhood solid tumours, especially neuroblastoma, medulloblastoma, ependymoma, rhabdomyosarcoma, and renal tumours, with emphasis on improving tumour control and refining multimodal treatment.
- High-risk neuroblastoma
- Medulloblastoma
- Ependymoma
- Childhood renal tumours
There is also involvement in therapeutic development for hepatoblastoma, germ cell tumours, and other paediatric embryonal malignancies.
Melanoma, head and neck cancer, and gastrointestinal oncology
Clinical research includes advanced melanoma, cutaneous squamous cell carcinoma, head and neck squamous cell carcinoma, biliary tract cancer, gastroesophageal junction adenocarcinoma, and hepatocellular carcinoma, reflecting interest in both curative-intent and advanced disease settings.
- Cutaneous melanoma
- Head and neck squamous cell carcinoma
- Biliary tract cancer
- Hepatocellular carcinoma
Work in this area includes evaluation of immunotherapy and combined treatment strategies across solid tumour types.
Benign inflammatory, dermatologic, and neurologic conditions
The investigator is also involved in research on non-oncologic therapeutic areas, including hidradenitis suppurativa, prurigo nodularis, vitiligo, scabies, bronchiectasis, relapsing multiple sclerosis, and chronic back pain.
- Hidradenitis suppurativa
- Prurigo nodularis
- Relapsing multiple sclerosis
- Bronchiectasis
This portfolio shows activity in symptom control, inflammatory disease management, and long-term disease-modifying treatment.
Critical care, stroke, and perioperative anticoagulation
Research involvement includes acute ischaemic stroke, high-risk transient ischaemic attack, factor Xa inhibitor-associated urgent intervention, status epilepticus, acute kidney injury, and critical illness, aligning with the department of anesthesiology and perioperative care.
- Acute ischaemic stroke
- Direct oral anticoagulant reversal
- Status epilepticus
- Acute kidney injury
Therapeutic interests include urgent procedural management, anticoagulation-related bleeding risk, and acute neurological intervention.
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