Ricardo A. J.
- Country
- The Netherlands
- Department
- Anasthesiology
Research Overview
Data & Insights
Has run more than one trial at 0 of 8 partner sites.
Specializations
Oncologic Therapeutics – Thoracic and Gastrointestinal Malignancies
The investigator concentrates on non‑small cell lung cancer and associated thoracic tumors.
- Targeted therapies in EGFR‑mutated NSCLC
- Immunotherapy for advanced lung carcinoma
- Combination regimens for metastatic pancreatic adenocarcinoma
- Precision medicine approaches in colorectal cancer
Clinical activities extend to pancreatic adenocarcinoma and metastatic colorectal disease.
Hematologic Malignancies
Research emphasis includes acute myeloid leukemia across molecular subtypes.
- Novel agents for AML with IDH mutations
- Maintenance strategies after stem cell transplantation
- Targeted therapy for diffuse large B‑cell lymphoma
- Immunomodulatory approaches in chronic lymphocytic leukemia
Studies also address diffuse large B‑cell lymphoma and related B‑cell disorders.
Cardiovascular and Metabolic Disorders
Focus is placed on atherosclerotic cardiovascular disease and its prevention.
- Risk reduction in high‑risk ASCVD populations
- Therapeutic optimization for heart failure with reduced ejection fraction
- Management of hypertension in diabetic cohorts
- Interventions for atrial fibrillation stroke prevention
Work also encompasses heart failure with reduced ejection fraction and hypertension management.
Neurodegenerative and Neuroendocrine Conditions
Investigation targets Alzheimer’s disease and related cognitive decline.
- Biomarker‑guided therapies for early Alzheimer’s
- Neuroprotective strategies in mild cognitive impairment
- Treatment of gastrointestinal neuroendocrine tumors
- Management of functional neuroendocrine syndromes
Additionally, the scope includes neuroendocrine tumors of gastrointestinal origin.
Autoimmune and Inflammatory Diseases
The investigator explores therapeutic strategies for rheumatoid arthritis and systemic autoimmunity.
- Biologic agents for moderate to severe RA
- Janus kinase inhibition in systemic lupus erythematosus
- Targeted treatments for inflammatory bowel disease
- Vasculitis management with novel immunomodulators
Efforts also cover inflammatory bowel disease and vasculitic syndromes.
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