Regis P. D. L.
- Country
- France
- Department
- Service d'Hematologie Greffe
Research Overview
- Comparison of ATG-Thymoglobulin Versus ATLG-Grafalon for GVHD Prophylaxis in Elderly AML or MDS Patients Undergoing Allogeneic HSCT with Reduced Intensity Conditioning
- Evaluation of REGN7257, an Anti-IL2RG Monoclonal Antibody, in Adults with Severe Aplastic Anemia Refractory or Relapsed to Immunosuppressive Therapy
- Evaluation of Long-Term Safety and Tolerability of Iptacopan in Patients with Paroxysmal Nocturnal Hemoglobinuria Post-Phase II/III Studies
Data & Insights
Has run more than one trial at 19 of 60 partner sites.
Specializations
Hematologic Malignancies
Clinical research activity is centered on acute myeloid leukemia, myelodysplastic syndromes, myelofibrosis, polycythemia vera, and other myeloproliferative neoplasms, with additional involvement in acute lymphoblastic leukemia, chronic lymphocytic leukemia, and multiple B-cell lymphomas.
- Acute myeloid leukemia
- Myelodysplastic syndromes
- Myelofibrosis
- B-cell lymphomas
Interest also extends to relapsed and refractory disease, allogeneic hematopoietic cell transplantation, graft-versus-host disease, and anemia associated with marrow failure disorders.
Solid Tumors and Melanoma
The investigator is involved in studies across melanoma, breast cancer, lung cancer, colorectal cancer, gastric and gastroesophageal cancers, prostate cancer, renal cell carcinoma, and urothelial carcinoma.
- Melanoma
- Breast cancer
- Colorectal cancer
- Renal cell carcinoma
Research also includes head and neck squamous cell carcinoma, esophageal cancer, pancreatic adenocarcinoma, and other advanced or metastatic solid tumors.
Immune-Mediated and Inflammatory Diseases
Clinical interests include atopic dermatitis, hidradenitis suppurativa, psoriasis, prurigo nodularis, systemic lupus erythematosus, and rheumatoid arthritis, alongside other autoimmune and autoinflammatory disorders.
- Atopic dermatitis
- Hidradenitis suppurativa
- Systemic lupus erythematosus
- Rheumatoid arthritis
Work in this area also covers vasculitis, sarcoidosis, inflammatory bowel disease, cutaneous lupus, and connective tissue disease.
Cardiovascular, Neurologic, and Critical Care Conditions
Research activity extends to atrial fibrillation, heart failure, acute coronary syndrome, myocardial infarction, stroke, and transient ischemic attack, reflecting a strong interest in cardiovascular prevention and outcomes.
- Atrial fibrillation
- Heart failure
- Stroke
- Myocardial infarction
Additional involvement includes migraine, Alzheimer’s disease, intensive care, sepsis-related infections, and ventilator-associated pneumonia.
Infectious Disease, Transplantation, and Rare Disorders
The investigator also contributes to studies in HIV-1 infection and prevention, COVID-19, invasive candidiasis, bacteremia, and antibiotic prophylaxis, with additional work in transplant-related and immunocompromised settings.
- HIV-1 infection
- COVID-19
- Invasive candidiasis
- Antibiotic prophylaxis
Rare disease interests include epidermolysis bullosa, Netherton syndrome, VEXAS syndrome, amyloidosis, and paroxysmal nocturnal hemoglobinuria.
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