Ramón L. B.
- Country
- Spain
- Department
- Allergology Department
Research Overview
- Long‑Term Safety of Repeated Subcutaneous ADX‑324, a Prekallikrein‑Targeting siRNA, in Adults With Hereditary Angioedema: Phase 3 Extension Study
- Evaluation of Long-Term Safety of Oral Deucrictibant (PHA-022121) for Acute Hereditary Angioedema Attacks in C1-Inhibitor Deficient Patients
- Long-Term Safety and Efficacy Evaluation of Donidalorsen in Hereditary Angioedema Prophylaxis: An Open-Label Study
Data & Insights
Has run more than one trial at 48 of 69 partner sites.
Specializations
Allergic Disease and Airway Inflammation
Clinical research activity in Allergology includes treatment-focused studies in allergic rhinitis, allergic rhinoconjunctivitis, atopic dermatitis, chronic urticaria, and asthma, with attention to both upper and lower airway disease.
- House dust mite sensitization
- Type 2 inflammatory asthma
- Chronic spontaneous urticaria
- Chronic rhinosinusitis with nasal polyps
Additional interest extends to thyroid eye disease and other immune-mediated allergic conditions.
Cardiovascular Medicine and Thromboembolic Prevention
The investigator is involved in studies addressing atrial fibrillation, heart failure, myocardial infarction, stroke prevention, and broader atherosclerotic cardiovascular disease, including lipid-related risk.
- Heart failure with reduced or preserved ejection fraction
- Acute coronary syndromes
- Ischemic stroke prevention
- Elevated lipoprotein(a)
Research also includes cardiac amyloidosis, hypertrophic cardiomyopathy, and anticoagulation-related cardiovascular risk.
Kidney Disease, Transplantation, and Renal Immunology
Work in nephrology spans chronic kidney disease, IgA nephropathy, lupus nephritis, renal transplantation, and post-transplant immune complications.
- Kidney transplant rejection
- Antibody-mediated rejection
- End-stage kidney disease
- Proteinuric renal disease
Therapeutic interest also covers Fabry disease, autoimmune renal disorders, and preservation of graft function.
Respiratory and Interstitial Lung Disorders
Clinical trial involvement includes idiopathic pulmonary fibrosis, progressive pulmonary fibrosis, interstitial lung disease, bronchiectasis, and severe infectious pulmonary syndromes.
- Fibrotic lung disease
- Chronic obstructive pulmonary disease
- Pulmonary sarcoidosis
- Severe community-acquired pneumonia
Additional focus appears in pulmonary hypertension linked to interstitial lung disease and other chronic respiratory conditions.
Autoimmune, Neuromuscular, and Inflammatory Conditions
The investigator’s therapeutic landscape also includes systemic autoimmune disease, myositis, multiple sclerosis, myasthenia gravis, and psoriatic disease, reflecting interest in immune-mediated disorders across organ systems.
- Dermatomyositis and polymyositis
- Systemic lupus erythematosus
- Generalized myasthenia gravis
- Multiple sclerosis
Related activity includes vitiligo, IgG4-related disease, and uveitis.
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