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Ramón B.

Country: Spain
Department: N/A

Research Overview

assignment

Clinical Trials ·

Effects of NNC0194-0499 alone and in combination with semaglutide, of semaglutide alone, and of cagrilintide alone and in combination with semaglutide on liver damage and alcohol use in people with alcohol-related liver disease

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Research Sites

Data & Insights

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Primary Speciality

Main therapeutic area

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Return Partnerships

Recurring site collaborations

Sites with multiple studies

Has run more than one trial at 0 of 43 partner sites.

Specializations

Advanced Solid Tumor Oncology

Focus on therapeutic strategies for non‑small cell lung cancer, breast cancer, and colorectal cancer with emphasis on metastatic and treatment‑resistant disease.

Targeted therapy in EGFR‑mutated NSCLC
CDK4/6 inhibitor combinations in HR+ HER2‑negative breast cancer
KRAS G12C inhibition in colorectal carcinoma
Immunotherapy approaches for metastatic melanoma
Combination regimens for HER2‑low breast tumors

Clinical investigations are conducted at Hospital Clinic de Barcelona and the Fundació de Recerca Biomèdica.

Hematologic Malignancies

Investigation of novel agents for acute myeloid leukemia, multiple myeloma, and lymphoma subtypes, particularly in relapsed or refractory settings.

Venetoclax‑based regimens for AML with high‑risk genetics
CAR‑T cell therapy evaluation in B‑cell lymphoma
Anti‑CD38 monoclonal antibodies in refractory multiple myeloma
PI3K inhibition in follicular lymphoma
Checkpoint blockade combined with hypomethylating agents in myelodysplastic syndromes

Trials address disease‑specific biomarkers and immune‑modulatory approaches.

Liver Disease and Hepatology

Research on acute‑on‑chronic liver failure, cirrhosis complications, and hepatocellular carcinoma, integrating anti‑inflammatory and antifibrotic therapies.

IL‑6 pathway inhibition in acute‑on‑chronic liver failure
Combination immunotherapy for advanced HCC
Antifibrotic agents targeting hepatic stellate cell activation
Biomarker‑driven stratification for liver transplant candidacy
Management of portal hypertension in decompensated cirrhosis

Studies aim to reduce mortality and improve quality of life in severe liver disease.

Infectious Diseases and Pulmonary Infections

Evaluation of treatments for nontuberculous mycobacterial lung infection and viral respiratory syndromes, including emerging pathogen management.

Long‑term antibiotic regimens for MAC disease
Adjunctive host‑directed therapy for severe viral pneumonia
Prophylactic strategies against opportunistic fungal infections
Immune‑modulation in chronic bronchiectasis with Pseudomonas colonisation
Vaccination impact studies in high‑risk respiratory populations

Research integrates microbiological diagnostics with personalized therapeutic plans.

Cardiovascular and Metabolic Disorders

Clinical focus on atrial fibrillation, atherosclerotic cardiovascular disease, and metabolic conditions such as type 2 diabetes mellitus.

Anticoagulant reversal protocols for urgent cardiac procedures
Risk‑reduction strategies in patients with high‑lipoprotein(a) levels
Combination lipid‑lowering therapy in ASCVD with obesity
Renal outcome monitoring in diabetic nephropathy
Device‑related thrombosis management after left atrial appendage closure

Efforts target prevention of cardiovascular events and metabolic complication mitigation.

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