Raffaella P. H.
- Country
- France
- Department
- Anesthésie Réanimation
Research Overview
Data & Insights
Has run more than one trial at 0 of 10 partner sites.
Specializations
Pediatric Neuro-Oncology
Focuses on malignant brain tumors in children, including diffuse intrinsic pontine glioma and other diffuse midline gliomas with H3K28M mutation or EZHIP positivity.
- Diffuse intrinsic pontine glioma (DIPG)
- Diffuse midline glioma H3K28M mutant
- EZHIP‑positive glioma
- Radiotherapy combined with targeted agents
- Progression‑free survival outcomes
Investigates novel therapeutic combinations for improved survival.
Pediatric Allergy and Immunotherapy
Addresses IgE‑mediated food allergy in early childhood, with emphasis on peanut desensitization strategies.
- Peanut allergy
- Oral immunotherapy
- Epicutaneous immunotherapy
- Desensitization efficacy
- Safety in young children
Evaluates long‑term tolerance induction.
Pediatric Anesthesia and Perioperative Sedation
Explores sedative and anxiolytic protocols to improve the peri‑operative experience of children undergoing general anesthesia.
- General anesthesia
- Sedative and anxiolytic agents
- Pre‑medication impact
- Childhood peri‑operative comfort
- Recovery metrics
Assesses pharmacologic premedication on postoperative outcomes.
Rare Metabolic and Neurological Disorders
Targets inherited leukodystrophies and neuroendocrine hyperplasia conditions affecting infants and children.
- Late infantile Metachromatic Leukodystrophy
- Neuroendocrine cell hyperplasia of infancy
- Intrathecal enzyme replacement
- Methylprednisolone pulse therapy
- Disease progression markers
Seeks disease‑modifying interventions for pediatric rare disorders.
Pediatric Respiratory and Pain Management
Covers chronic airway disease and acute severe pain in children, integrating biologic therapy and intranasal analgesics.
- Severe asthma
- Wheezing disorders
- Biologic dupilumab
- Intranasal sufentanil
- Intranasal ketamine
- Acute trauma‑related pain
Focuses on rapid analgesia and control of airway inflammation in pediatric patients.
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