Rafael B. E.
- Country
- Spain
- Department
- Dermatology
Research Overview
- Phase 3 Extension Study of Long-Term Safety and Efficacy of Remibrutinib in Adults With Moderate to Severe Hidradenitis Suppurativa
- Phase 3 Double‑Blind Vehicle‑Controlled Trial of Topical Delgocitinib Cream in Adult Women with Lichen Sclerosus: 12‑Week Efficacy and 40‑Week Safety Evaluation
- Efficacy and Safety Evaluation of JNJ-77242113 Versus Placebo and Deucravacitinib in Moderate to Severe Plaque Psoriasis: A Phase 3 Randomized Controlled Trial
Data & Insights
Has run more than one trial at 174 of 369 partner sites.
Specializations
Oncodermatology and Skin Cancer
Clinical research activity includes trials in cutaneous squamous cell carcinoma, melanoma, advanced solid tumors, and head and neck squamous cell carcinoma, with attention to systemic therapies used in advanced malignancy.
- Melanoma
- Cutaneous squamous cell carcinoma
- Advanced solid tumors
- Head and neck squamous cell carcinoma
Work in this area also extends to biomarker-defined cancer populations and treatment-resistant disease settings.
Inflammatory Skin Disease
Research interests cover chronic immune-mediated dermatologic disorders, especially atopic dermatitis, psoriasis, hidradenitis suppurativa, prurigo nodularis, and bullous pemphigoid.
- Atopic dermatitis
- Plaque psoriasis
- Hidradenitis suppurativa
- Prurigo nodularis
These trials reflect a therapeutic focus on immune modulation for persistent inflammatory skin conditions.
Autoimmune and Connective Tissue Disorders
Clinical involvement includes systemic lupus erythematosus, psoriatic arthritis, juvenile idiopathic arthritis, rheumatoid arthritis, systemic sclerosis, and Sjögren’s syndrome.
- Systemic lupus erythematosus
- Psoriatic arthritis
- Juvenile idiopathic arthritis
- Systemic sclerosis
Research also spans overlapping inflammatory syndromes requiring long-term disease control.
Gastrointestinal and Hepatic Immunology
Trial activity covers Crohn’s disease, ulcerative colitis, primary biliary cholangitis, non-alcoholic steatohepatitis, and hepatocellular carcinoma.
- Crohn’s disease
- Ulcerative colitis
- Primary biliary cholangitis
- Hepatocellular carcinoma
This includes both inflammatory bowel disease and liver-related therapeutic domains.
Pediatric and Rare Disease Dermatologic Interest
Additional research areas include juvenile psoriatic arthritis, thyroid eye disease, allergic rhinitis, dry eye disease, and mucosal inflammatory disorders with dermatologic relevance.
- Juvenile psoriatic arthritis
- Thyroid eye disease
- Allergic rhinitis
- Dry eye disease
These studies connect skin care with pediatric, allergic, and rare inflammatory conditions.
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