Quentin P.
- Country
- Belgium
- Department
- Hemato Oncology
Research Overview
- Evaluation of Blinatumomab, Isatuximab, and Ponatinib in Frontline Therapy for Adults with Acute Lymphoblastic Leukemia and T-Lymphoblastic Lymphoma
- HOVON 181 AML: Bleximenib or Placebo in Combination with Standard Induction and Consolidation Therapy followed by Maintenance for the Treatment of Patients with Newly Diagnosed KMT2A-rearranged or NPM1-mutant Acute Myeloid Leukemia Eligible for Intensive Chemotherapy: a double-blind phase 3 study
- Linvoseltamab Monotherapy and Linvoseltamab plus Carfilzomib versus Standard of Care in Patients with Relapsed/Refractory Multiple Myeloma
Data & Insights
Has run more than one trial at 34 of 223 partner sites.
Specializations
Hemato-oncology
Clinical research in hemato-oncology includes acute lymphoblastic leukemia, acute myeloid leukemia, lymphoblastic lymphoma, peripheral T-cell lymphoma, follicular lymphoma, small lymphocytic lymphoma, and multiple myeloma, with attention to both adult and pediatric disease.
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Peripheral T-cell lymphoma
- Follicular lymphoma
The therapeutic focus also extends to allogeneic hematopoietic stem cell transplantation, immunotherapy, and targeted approaches in relapsed or high-risk hematologic malignancies.
Breast and gynecologic oncology
Research activity in breast cancer covers triple-negative breast cancer, hormone receptor-positive and HER2-negative breast cancer, advanced breast cancer, and early breast cancer with recurrence risk, alongside endometrial cancer, ovarian cancer, and cervical cancer.
- Triple-negative breast cancer
- Hormone receptor-positive breast cancer
- Endometrial cancer
- Ovarian cancer
Therapeutic interests include antibody-drug conjugates, endocrine-based treatment strategies, and postoperative disease control in solid tumors of the breast and female reproductive tract.
Gastroenterology and inflammatory disease
Clinical work in inflammatory bowel disease includes Crohn’s disease and ulcerative colitis, with additional interest in gastroparesis, chronic hepatitis B infection, and metabolic liver disease.
- Crohn’s disease
- Ulcerative colitis
- Gastroparesis
- Chronic hepatitis B infection
The therapeutic emphasis includes biologic therapy, targeted immunomodulation, and long-term disease control in chronic gastrointestinal inflammation.
Thoracic and gastrointestinal solid tumors
Research involvement spans non-small cell lung cancer, small cell lung cancer, esophageal squamous cell carcinoma, gastric cancer, gastroesophageal junction adenocarcinoma, pancreatic adenocarcinoma, and colorectal cancer.
- Non-small cell lung cancer
- Small cell lung cancer
- Gastric cancer
- Pancreatic adenocarcinoma
Therapeutic interest centers on immunotherapy, targeted therapy, and treatment optimization for advanced and metastatic solid tumors.
Cardiovascular, neurologic, and renal medicine
Clinical research also covers acute ischemic stroke, atrial fibrillation, acute coronary syndrome, heart failure, hypertension, intracerebral haemorrhage, chronic kidney disease, and proteinuria.
- Acute ischemic stroke
- Atrial fibrillation
- Hypertension
- Chronic kidney disease
The therapeutic scope includes stroke prevention, antithrombotic therapy, blood pressure control, and renal protection in vascular and kidney disease.
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