Przemysław A.
- Country
- Poland
- Department
- Dzial Badan Klinicznych
Research Overview
- Efficacy and Safety of Capivasertib Plus Abiraterone in PTEN-Deficient Metastatic Hormone-Sensitive Prostate Cancer: A Phase III Randomized, Double-Blind, Placebo-Controlled Trial
- Phase 3 Randomized Study of PF-06821497 with Enzalutamide vs. Enzalutamide or Docetaxel in Metastatic Castration-Resistant Prostate Cancer Post-Abiraterone
- Phase 3 Randomized Double-Blind Study of PF-06821497 and Enzalutamide in Metastatic Castration-Resistant Prostate Cancer
Data & Insights
Has run more than one trial at 57 of 184 partner sites.
Specializations
Rheumatology and Connective Tissue Diseases
Clinical research activity centers on inflammatory joint and systemic autoimmune disorders, with involvement in rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, and systemic lupus erythematosus. The portfolio also includes broader connective tissue disease and immune-mediated disease programs.
- Rheumatoid arthritis
- Psoriatic arthritis
- Axial spondyloarthritis
- Systemic lupus erythematosus
Additional interests extend to systemic sclerosis, Sjögren’s syndrome, and related autoimmune phenotypes that require targeted anti-inflammatory and immunomodulatory therapies.
Dermatology and Immune-Mediated Skin Disease
The investigator is active in trials addressing chronic inflammatory skin conditions, especially atopic dermatitis, psoriasis, hidradenitis suppurativa, alopecia areata, and prurigo nodularis. This area also includes difficult-to-control manifestations such as palmoplantar pustulosis and chronic urticaria.
- Atopic dermatitis
- Psoriasis
- Hidradenitis suppurativa
- Alopecia areata
Therapeutic interest spans biologic and targeted approaches for persistent inflammatory skin disease, including conditions with overlapping dermatologic and systemic immune features.
Myasthenia Gravis and Neuromuscular Disorders
Research involvement includes antibody-mediated neuromuscular disease, with focus on generalized myasthenia gravis, ocular myasthenia gravis, and acetylcholine receptor antibody-defined subtypes. The portfolio also touches on broader neuropathic and demyelinating disorders.
- Generalized myasthenia gravis
- Ocular myasthenia gravis
- Acetylcholine receptor antibody subtypes
- Chronic inflammatory demyelinating polyneuropathy
Areas of interest include therapies aimed at reducing autoimmune neuromuscular dysfunction and improving symptom control in chronic antibody-driven disease.
Hematology and Oncology
The clinical landscape includes studies in myelofibrosis, myelodysplastic syndrome, acute myeloid leukemia, multiple myeloma, and lymphoma. Solid tumor involvement also covers breast cancer, prostate cancer, non-small cell lung cancer, and renal cell carcinoma.
- Myelofibrosis
- Acute myeloid leukemia
- Multiple myeloma
- Breast cancer
Research activity also includes bladder cancer and other advanced malignancies, reflecting interest in both hematologic and solid-tumor treatment innovation.
Cardiometabolic, Pulmonary, and Musculoskeletal Pain
Additional trial involvement spans atherosclerotic cardiovascular disease, myocardial infarction, hypertension, obesity, and type 2 diabetes mellitus, alongside respiratory conditions such as chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, and severe eosinophilic asthma.
- Atherosclerotic cardiovascular disease
- Myocardial infarction
- Chronic obstructive pulmonary disease
- Idiopathic pulmonary fibrosis
Musculoskeletal and pain-focused interests include osteoarthritis, chronic low back pain, knee pain, and diabetic peripheral neuropathy, together with related functional and inflammatory pain syndromes.
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