Pietro D.
- Country
- Italy
- Department
- U.O. Malattie Neuromuscolari e Neuroimmunologia IRCCS
Research Overview
- Phase 3 Randomized Double-Blind Trial of Riliprubart Versus Intravenous Immunoglobulin in Chronic Inflammatory Demyelinating Polyneuropathy
- Efficacy and Safety Evaluation of Riliprubart in Refractory Chronic Inflammatory Demyelinating Polyneuropathy: A Phase 3 Double-Blind, Placebo-Controlled Study
- ZANUBRUTINIB, A SECOND GENERATION BTK INHIBITOR, IN ANTI-MAG ANTIBODY NEUROPATHY: A PHASE II ITALIAN MULTICENTER CLINICAL TRIAL (MAZINGA)
Data & Insights
Has run more than one trial at 30 of 78 partner sites.
Specializations
Neuroimmunology and Neuromuscular Disease
The investigator is involved in clinical research on immune-mediated disorders of the nervous system and peripheral muscle, with a clear focus on conditions that affect neuromuscular function and immune regulation.
- Chronic inflammatory demyelinating polyradiculoneuropathy
- Multifocal motor neuropathy
- Idiopathic inflammatory myopathy
- Dermatomyositis
- Immune-mediated necrotizing myopathy
Research activity also extends to broader autoimmune neuromuscular disease and related immune system disorders, reflecting interest in therapies that modify inflammatory and antibody-mediated pathology.
Inflammatory Bowel Disease
Clinical trial involvement includes therapeutic development for chronic gastrointestinal inflammation, particularly disorders marked by relapsing mucosal injury and immune dysregulation.
- Crohn's disease
- Ulcerative colitis
- Fibrostenotic Crohn’s disease
- Fistulizing perianal Crohn's disease
- Eosinophilic esophagitis
The therapeutic landscape includes gastrointestinal immunology and treatment strategies aimed at controlling inflammation, bowel urgency, and disease recurrence in chronic intestinal disease.
Oncology and Hematologic Malignancies
The investigator participates in studies across solid tumors and blood cancers, with emphasis on advanced disease settings and molecularly defined malignancies.
- Non-small cell lung cancer
- Breast cancer
- Hepatocellular carcinoma
- Diffuse large B-cell lymphoma
- Multiple myeloma
Additional interests include head and neck squamous cell carcinoma, ovarian cancer, pancreatic cancer, and myelodysplastic syndromes, supporting therapeutic innovation in both targeted and immune-based oncology.
Hepatology and Metabolic Liver Disease
Research activity also covers chronic liver disorders linked to inflammation, fibrosis, and metabolic dysfunction, including conditions with progressive hepatic injury.
- Non-alcoholic steatohepatitis
- Metabolic dysfunction-associated steatohepatitis
- Primary biliary cholangitis
- Primary sclerosing cholangitis
- Hepatocellular carcinoma
The therapeutic focus includes fibrosis-related liver disease, cholestatic disorders, and advanced liver cancer, with attention to interventions that address progression and symptom burden.
Autoimmune and Immune-Mediated Disorders
The investigator is also engaged in trials spanning systemic inflammatory diseases that require targeted immune modulation across multiple organ systems.
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Psoriatic arthritis
- Atopic dermatitis
- Hidradenitis suppurativa
Related interests include hemophilia, antiphospholipid syndrome, and other immune-mediated conditions, highlighting a broad commitment to therapies for chronic inflammatory disease.
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