Poli M.
- Country
- France
- Department
- Department of Ophthalmology
Research Overview
Data & Insights
Has run more than one trial at 1 of 26 partner sites.
Specializations
Retinal Degeneration and Geographic Atrophy
Clinical activity centers on age-related macular degeneration with a strong focus on geographic atrophy, including dry AMD with atrophic change and related lesion progression. The investigator is involved in studies addressing vision preservation and long-term disease control in advanced retinal degeneration.
- Geographic atrophy secondary to age-related macular degeneration
- Dry AMD with geographic atrophy
- Atrophic lesion growth
- Visual function in degenerative macular disease
This area includes interest in therapeutic strategies aimed at slowing retinal tissue loss and maintaining central vision in chronic macular disease.
Neovascular Retinal Disease
The investigator is active in neovascular age-related macular degeneration, choroidal neovascularization secondary to pathologic myopia, and related exudative retinal disorders. The therapeutic emphasis is on controlling abnormal vascular activity and preserving visual acuity in sight-threatening macular disease.
- Wet AMD
- Choroidal neovascularization
- Pathologic myopia
- Intravitreal anti-angiogenic therapy
Clinical interests also extend to treatment burden and durability of response in chronic retinal vascular disease.
Macular Edema and Retinal Vein Occlusion
Research involvement includes diabetic macular oedema and central retinal vein occlusion, with attention to visual recovery and retinal fluid control. The investigator contributes to therapeutic evaluation in ischemic and edema-driven macular pathology.
- Diabetic macular oedema
- Central retinal vein occlusion
- Visual acuity outcomes
- Retinal edema management
These activities reflect a focus on maintaining retinal structure and function in vascular complications of eye disease.
Glaucoma and Ocular Hypertension
The investigator is engaged in studies of open-angle glaucoma and ocular hypertension, with particular attention to intraocular pressure control and sustained therapeutic effect. This area reflects interest in chronic optic nerve risk reduction and pressure-lowering treatment options.
- Open-angle glaucoma
- Ocular hypertension
- Intraocular pressure reduction
- Long-acting ocular therapy
Clinical work in this domain is directed toward stabilizing pressure-related disease progression in anterior segment and optic nerve disorders.
Innovative Ocular Therapeutics
Across retinal and glaucomatous disease, the investigator is involved in therapies that include complement inhibition, anti-VEGF treatment, intravitreal implants, and gene-based ophthalmic approaches. The therapeutic landscape also includes agents targeting retinal inflammation and neuroprotection.
- Complement-mediated retinal disease
- Intravitreal sustained-release therapy
- Anti-VEGF combination treatment
- Gene therapy for retinal disease
These interests place emphasis on expanding treatment options for chronic retinal and glaucoma-related conditions in ophthalmology.
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