Pierre-Jean S.
- Country
- France
- Department
- N/A
Research Overview
- Evaluation of Baxdrostat and Dapagliflozin on Chronic Kidney Disease Progression in Hypertensive Patients: A Randomized, Double-Blind, Active-Controlled Phase III Trial
- Efficacy and Safety of Baxdrostat and Dapagliflozin on Renal and Cardiovascular Outcomes in Chronic Kidney Disease with Hypertension
- Efficacy and Safety of Cagrilintide and Semaglutide in Patients with Type 2 Diabetes, Chronic Kidney Disease, and Overweight or Obesity
Data & Insights
Has run more than one trial at 102 of 304 partner sites.
Specializations
Hematologic malignancies and bone marrow disorders
Clinical research activity includes a strong focus on acute leukemias, lymphomas, multiple myeloma, and myelodysplastic syndromes, with additional interest in related precursor and relapsed/refractory hematologic conditions.
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Diffuse large B-cell lymphoma
- Multiple myeloma
- Myelodysplastic syndromes
Additional involvement extends to Waldenström macroglobulinemia, myelofibrosis, plasma cell leukemia, and post-transplant hematologic complications.
Solid tumors and gastrointestinal oncology
The investigator is engaged in a broad oncologic portfolio centered on colorectal cancer, gastric and gastroesophageal junction cancers, pancreatic cancer, biliary tract cancer, and hepatocellular carcinoma.
- Colorectal cancer
- Gastric cancer
- Pancreatic adenocarcinoma
- Cholangiocarcinoma
- Hepatocellular carcinoma
Research also covers esophageal cancer, gastrointestinal stromal tumor, neuroendocrine carcinoma, and sarcoma, reflecting interest in advanced and biomarker-defined solid tumors.
Breast cancer, gynecologic oncology, and genitourinary tumors
Clinical work includes studies in breast cancer across hormone receptor-positive, HER2-positive, and triple-negative subtypes, alongside ovarian cancer, endometrial cancer, and cervical cancer.
- HER2-positive breast cancer
- Triple-negative breast cancer
- Endometrial cancer
- Ovarian cancer
- Urothelial carcinoma
There is also involvement in prostate cancer, renal cell carcinoma, and bladder cancer, with attention to recurrent, metastatic, and biomarker-selected disease.
Cardiovascular, stroke, and critical care medicine
The investigator’s portfolio includes acute myocardial infarction, heart failure, atrial fibrillation, atherosclerotic cardiovascular disease, and stroke, as well as conditions linked to thrombotic and vascular risk.
- Acute coronary syndrome
- Ischemic stroke
- Heart failure
- Atrial fibrillation
- Hypertension
Additional interest extends to septic shock, hospital-acquired pneumonia, out-of-hospital cardiac arrest, and intensive care management.
Autoimmune, renal, and rare inflammatory diseases
Research activity also spans systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, giant cell arteritis, and ANCA-associated vasculitis, with a parallel focus on inflammatory and immune-mediated disorders.
- Systemic lupus erythematosus
- Lupus nephritis
- Rheumatoid arthritis
- Giant cell arteritis
- Chronic kidney disease
Further involvement includes pulmonary arterial hypertension, amyloidosis, kidney transplantation, and inflammatory bowel disease.
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