Philippine R.
- Country
- France
- Department
- Hématologie
Research Overview
- Comparative Efficacy of Amoxicillin-Clavulanic Acid Versus Amoxicillin-Clavulanic Acid Plus Ciprofloxacin in Chemotherapy-Induced Fever in Adult Hematology Patients
- Study PACIFIC: Fixed duration treatment with combined pirtobrutinib and short course immuno-chemotherapy in fit patients with previously untreated symptomatic chronic lymphocytic leukemia (CLL). A phase II FILO trial
Data & Insights
Has run more than one trial at 3 of 42 partner sites.
Specializations
Hematologic malignancies
Clinical research in myelodysplastic syndromes, multiple myeloma, follicular lymphoma, and chronic lymphocytic leukemia, with additional interest in treatment approaches for haematological disorders associated with infection risk and anemia.
- Myelodysplastic syndromes
- Multiple myeloma
- Follicular lymphoma
- Chronic lymphocytic leukemia
Research activity also includes supportive and disease-control strategies relevant to transfusion dependence, neutropenia, and refractory cytopenias.
Gastrointestinal and hepatobiliary oncology
Investigator involvement covers colorectal cancer, advanced biliary tract cancer, hepatocellular carcinoma, and anal squamous cell carcinoma, with attention to both resected and metastatic disease settings.
- Colorectal cancer
- Advanced biliary tract cancer
- Hepatocellular carcinoma
- Locally advanced anal squamous cell carcinoma
The therapeutic landscape includes adjuvant, first-line, and maintenance strategies aimed at improving disease control and recurrence prevention.
Immune-mediated gastrointestinal disease
Research extends to Crohn’s disease and ulcerative colitis, with a clear focus on biologic and targeted therapies for persistent inflammatory activity and loss of response.
- Crohn’s disease
- Ulcerative colitis
- Biologic therapy
- Targeted anti-inflammatory treatment
Clinical interests include remission maintenance, biomarker-guided management, and optimization of treatment sequencing in chronic intestinal inflammation.
Dermatologic and immune-mediated disorders
The investigator is involved in studies of moderate-to-severe plaque psoriasis and prurigo nodularis, reflecting interest in chronic inflammatory skin disease and symptom burden reduction.
- Moderate-to-severe plaque psoriasis
- Prurigo nodularis
- Immune-mediated skin disease
- Long-term symptom control
These trials align with therapeutic development for persistent pruritus, cutaneous inflammation, and quality-of-life impairment.
Solid tumors and multimodal cancer therapy
Additional research spans melanoma, head and neck squamous cell carcinoma, non-small cell lung cancer, ovarian cancer, and breast cancer, including resected, locally advanced, and metastatic settings.
- Melanoma
- Head and neck squamous cell carcinoma
- Non-small cell lung cancer
- Ovarian cancer
Work in this area includes immunotherapy, adjuvant treatment, and combined-modality oncology for recurrence reduction and survival improvement.
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