Petra S. R.
- Country
- Germany
- Department
- Hautklinik und Poliklinik/Clinical Research Center
Research Overview
- A phase 2B, multicenter, randomized, double-blind, placebo-controlled, dose-finding, efficacy and safety study of HRO350 in subjects with mild-to-moderate psoriasis (the ‘HeROPA’ study)
- A Phase 2 Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of LAD328 in Adults with Moderate to Severe Hidradenitis Suppurativa
- Efficacy and Safety of Zasocitinib in Pediatric Participants with Moderate-to-Severe Plaque Psoriasis: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial
Data & Insights
Has run more than one trial at 375 of 660 partner sites.
Specializations
Dermatology and Immune-Mediated Skin Disease
Clinical research activity includes a strong focus on inflammatory and autoimmune skin disorders, with involvement in atopic dermatitis, psoriasis, hidradenitis suppurativa, prurigo nodularis, urticaria, vitiligo, and bullous pemphigoid.
- Atopic dermatitis
- Plaque psoriasis
- Hidradenitis suppurativa
- Prurigo nodularis
- Vitiligo
Work in this domain also extends to chronic pruritic and immune-driven skin conditions, supporting therapeutic development in dermatologic inflammation.
Autoimmunity, Rheumatology, and Systemic Inflammatory Disease
The investigator is active in systemic immune disorders, particularly systemic lupus erythematosus, lupus nephritis, systemic sclerosis, idiopathic inflammatory myopathy, rheumatoid arthritis, and Sjögren’s disease.
- Systemic lupus erythematosus
- Lupus nephritis
- Systemic sclerosis
- Idiopathic inflammatory myopathy
- Rheumatoid arthritis
Additional interests include autoimmune hepatitis, primary sclerosing cholangitis, primary biliary cholangitis, and ANCA-associated vasculitis.
Oncology and Hematologic Malignancies
Research involvement spans solid tumors and blood cancers, with emphasis on non-small cell lung cancer, melanoma, breast cancer, gastric and gastroesophageal junction cancer, hepatocellular carcinoma, and colorectal cancer.
- Non-small cell lung cancer
- Melanoma
- Breast cancer
- Hematologic malignancies
- Hepatocellular carcinoma
Hematology-focused activity includes acute leukemias, lymphomas, multiple myeloma, myelodysplastic syndromes, and chronic myeloid leukemia.
Nephrology, Transplantation, and Cardiometabolic Disease
Clinical trial engagement also covers kidney and transplant-related conditions, including chronic kidney disease, IgA nephropathy, focal segmental glomerulosclerosis, kidney transplant rejection, and delayed graft function.
- Chronic kidney disease
- IgA nephropathy
- Focal segmental glomerulosclerosis
- Kidney transplant rejection
- Delayed graft function
Related activity includes portal hypertension, liver cirrhosis, metabolic dysfunction-associated steatohepatitis, atrial fibrillation, and atherosclerotic cardiovascular disease.
Pediatric and Rare Disease Therapeutics
Several studies involve pediatric and uncommon disorders, including acute lymphoblastic leukemia, neuroblastoma, medulloblastoma, atypical teratoid/rhabdoid tumor, cystic fibrosis, and phenylketonuria.
- Acute lymphoblastic leukemia
- Neuroblastoma
- Medulloblastoma
- Cystic fibrosis
- Rare genetic disease
Interest also extends to thyroid eye disease, neurotrophic keratopathy, diabetic retinopathy, Alzheimer’s disease, and Parkinson’s disease.
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