Petar P.
- Country
- Bulgaria
- Department
- Department of Medical Oncology and Oncological Diseases in Hematology
Research Overview
- A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Azetukalner in Patients with Bipolar Depression
- A Long-term, Open-Label Study to Evaluate the Safety, Tolerability, and Efficacy of Azetukalner in Patients with Bipolar I or II Depression
- Phase III Randomized Open‑Label Study of Atezolizumab + Lenvatinib or Sorafenib vs Lenvatinib/Sorafenib Alone in Previously Treated Unresectable HCC
Data & Insights
Has run more than one trial at 109 of 328 partner sites.
Specializations
Psychiatry and Neurocognitive Disorders
Clinical research activity in psychiatry includes treatment development for schizophrenia, major depressive disorder, bipolar depression, generalized anxiety disorder, and insomnia disorder, with attention to both adult and adolescent populations.
- Schizophrenia
- Major depressive disorder
- Bipolar depression
- Insomnia disorder
- Lewy body dementia psychosis
Additional interest extends to agitation in dementia, cognitive disorder, and Tourette’s disorder, reflecting involvement in neuropsychiatric conditions with unmet therapeutic need.
Breast Cancer and Hormone-Responsive Malignancies
Research involvement is strongly centered on breast cancer, especially hormone receptor-positive, HER2-negative, HER2-positive, and metastatic breast cancer, alongside early and locally advanced disease settings.
- ER+/HER2- advanced breast cancer
- HER2-positive breast cancer
- Metastatic breast cancer
- Early breast cancer
- PIK3CA-mutant breast cancer
The therapeutic landscape also includes endocrine therapy, CDK4/6 inhibition, and recurrence prevention in hormone-driven disease.
Thoracic Oncology and Lung Cancer
Clinical trial activity covers multiple forms of lung cancer, including non-small cell lung cancer, small cell lung cancer, extensive-stage small cell lung cancer, and limited-stage small-cell lung cancer.
- Non-small cell lung cancer
- Small cell lung cancer
- Extensive-stage small cell lung cancer
- KRAS G12C-mutant NSCLC
- HER2-mutant NSCLC
Other areas include locally advanced disease, metastatic disease, and treatment strategies involving immunotherapy and targeted therapy.
Genitourinary and Prostate Cancer
Research focus includes prostate cancer, particularly metastatic castration-resistant prostate cancer, metastatic castration-sensitive prostate cancer, and metastatic hormone-sensitive prostate cancer.
- Metastatic castration-resistant prostate cancer
- Metastatic castration-sensitive prostate cancer
- Metastatic hormone-sensitive prostate cancer
- Bladder cancer
- Renal cell carcinoma
Additional involvement extends to urothelial cancer and renal cell carcinoma, with emphasis on advanced and treatment-resistant genitourinary malignancies.
Ovarian, Gastrointestinal, and Other Solid Tumors
The oncology portfolio also includes ovarian cancer, colorectal cancer, head and neck squamous cell carcinoma, cutaneous squamous cell carcinoma, and other solid tumors.
- Ovarian cancer
- Colorectal cancer
- Head and neck squamous cell carcinoma
- Cutaneous squamous cell carcinoma
- Advanced solid tumors
Therapeutic interests also include ovarian cancer recurrence, gBRCA-mutated malignancies, and broader targeted anticancer treatment across advanced solid tumor settings.
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