PERROUIN-VERBE M. A.
- Country
- France
- Department
- Service d’Urologie
Research Overview
- Evaluation of a Drug Combination for Treatment of Bacterial Urinary Infection in Patients with E. coli Urinary Tract Infection
- Efficacy of OM-89 Versus Placebo in Reducing Antibiotic Use for Recurrent Urinary Tract Infections in Patients with Neurogenic Bladder: A Randomized Trial
- Evaluation of Peri-Operative Antibiotic Strategy Versus Antibiotic Sparing in Asymptomatic Bacteriuria with Botulinum Toxin A in MS and SCI Patients
Data & Insights
Has run more than one trial at 7 of 13 partner sites.
Specializations
Urologic Oncology
Clinical research in urothelial carcinoma, bladder cancer, muscle-invasive bladder cancer, and other genitourinary malignancies is a major area of interest, with attention to advanced and metastatic disease, high-risk recurrence, and treatment-resistant settings.
- Urothelial carcinoma
- Bladder cancer
- Prostate cancer
- Renal cell carcinoma
- Kidney transplantation
The investigator is also involved in studies addressing prostate cancer and renal malignancies, extending the therapeutic focus across both localized and advanced urologic disease.
Hematologic Malignancies
Research activity includes a broad spectrum of blood cancers, especially acute myeloid leukemia, acute lymphoblastic leukemia, myelodysplastic syndromes, multiple myeloma, and lymphomas, with interest in both newly diagnosed and relapsed or refractory disease.
- Acute myeloid leukemia
- Acute lymphoblastic leukemia
- Multiple myeloma
- Diffuse large B-cell lymphoma
- Myelodysplastic syndromes
There is also involvement in allogeneic hematopoietic stem cell transplantation and graft-versus-host disease, supporting innovation in complex hematology care.
Solid Tumors and Thoracic Oncology
The clinical portfolio covers non-small cell lung cancer, small cell lung cancer, head and neck squamous cell carcinoma, colorectal cancer, gastric cancer, and hepatocellular carcinoma, with emphasis on advanced, metastatic, and biomarker-defined disease.
- Non-small cell lung cancer
- Small cell lung cancer
- Head and neck squamous cell carcinoma
- Colorectal cancer
- Hepatocellular carcinoma
Research also extends to melanoma, pancreatic cancer, and neuroendocrine tumors, reflecting a strong focus on difficult-to-treat solid malignancies.
Immune-Mediated and Inflammatory Diseases
Therapeutic interest includes systemic lupus erythematosus, vasculitis, rheumatoid arthritis, Crohn’s disease, ulcerative colitis, and atopic dermatitis, together with other chronic immune-mediated conditions.
- Systemic lupus erythematosus
- ANCA-associated vasculitis
- Rheumatoid arthritis
- Crohn’s disease
- Atopic dermatitis
Additional work in mucous membrane pemphigoid, psoriasis, and hidradenitis suppurativa broadens the investigator’s involvement in inflammatory skin and systemic autoimmune disorders.
Transplantation, Renal, and Supportive Care
Clinical interests also include kidney disease, IgA nephropathy, lupus nephritis, kidney transplantation, and post-transplant complications, alongside supportive care topics relevant to medically complex patients.
- IgA nephropathy
- Lupus nephritis
- Kidney transplantation
- Post-transplant complications
- Chronic kidney disease
Research further spans cardiovascular disease, heart failure, and infectious complications in vulnerable populations, including patients receiving intensive oncologic or transplant-related care.
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