Pawel O.
- Country
- Poland
- Department
- n/a
Research Overview
- Phase II Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Vixarelimab in Patients with Moderate to Severe Ulcerative Colitis
- Comparative Efficacy, Safety, and Immunogenicity of Intravenous AVT16 Versus Vedolizumab in Adults with Moderate to Severe Active Ulcerative Colitis
- A randomized, double-blind, multicenter phase 3 study in patients with moderately to severely active ulcerative colitis (UC) to compare the efficacy, safety and immunogenicity of PB016 and Entyvio® for the induction and maintenance of clinical response and remission. (UCESIVE)
Data & Insights
Has run more than one trial at 49 of 184 partner sites.
Specializations
Retinal Vascular and Macular Disease
Pawel Oleksy is involved in clinical research focused on diabetic macular edema, macular edema secondary to retinal vein occlusion, and wet age-related macular degeneration, with additional interest in vision-threatening retinal disorders affecting central retinal function.
- Best-corrected visual acuity
- Intravitreal therapy
- Retinal vein occlusion
- Age-related macular degeneration
His trial portfolio includes evaluation of ocular treatments designed to preserve or improve visual outcomes in chronic retinal disease.
Geographic Atrophy and Degenerative Retinal Conditions
His research landscape also includes geographic atrophy and geographic atrophy secondary to age-related macular degeneration, reflecting sustained interest in progressive degenerative retinal disease and therapies aimed at slowing structural retinal damage.
- Geographic atrophy
- Retinal degeneration
- Vision preservation
- Complement-targeted ophthalmic therapy
These studies align with therapeutic strategies intended to address long-term retinal deterioration and central vision loss.
Inflammatory Bowel Disease
Pawel Oleksy is active in trials for ulcerative colitis, including moderate to severe active ulcerative colitis, with a clear therapeutic focus on controlling intestinal inflammation and improving disease remission outcomes.
- Ulcerative colitis
- Clinical remission
- Induction therapy
- Inflammatory bowel disease
His involvement spans investigational and comparator biologic approaches used in chronic gastrointestinal immune-mediated disease.
Biologic and Biosimilar Therapeutics
His clinical trial activity includes assessment of biosimilar and biologic therapies, with interest in treatment comparability, safety, and effectiveness across immune-mediated and ophthalmic indications.
- Biosimilar development
- Biologic comparability
- Therapeutic equivalence
- Ophthalmic and gastroenterology therapeutics
This includes research on agents intended to broaden access to established treatment classes in both eye disease and ulcerative colitis.
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