Pau A. C.
- Country
- Spain
- Department
- Hematology Department
Research Overview
- Evaluation of Venetoclax Combined With Polatuzumab Vedotin, Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone in Untreated BCL-2 IHC-Positive DLBCL Patients
- Evaluation of Adverse Events, Pharmacokinetics, and Disease Activity of Oral ABBV-101 in Adult Patients with Select B-Cell Malignancies
- Evaluation of ABBV-319 Pharmacokinetics, Safety, and Efficacy in Adults with Relapsed/Refractory Diffuse Large B-cell Lymphoma, Follicular Lymphoma, or Chronic Lymphocytic Leukemia
Data & Insights
Has run more than one trial at 126 of 309 partner sites.
Specializations
Hematologic malignancies and cellular therapies
Clinical research in lymphoid and myeloid cancers spans acute myeloid leukemia, acute lymphoblastic leukemia, diffuse large B-cell lymphoma, follicular lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, multiple myeloma, and myelodysplastic syndromes, with additional interest in graft-versus-host disease and hematopoietic stem cell transplantation.
- Acute myeloid leukemia
- Chronic lymphocytic leukemia
- Multiple myeloma
- Diffuse large B-cell lymphoma
- Graft-versus-host disease
The portfolio also includes relapsed or refractory blood cancers and B-cell malignancies, reflecting a strong therapeutic focus on advanced hematologic disease.
Solid tumors and biomarker-driven oncology
The investigator is active in a broad range of solid tumor studies, with emphasis on non-small cell lung cancer, small cell lung cancer, breast cancer, colorectal cancer, urothelial carcinoma, renal cell carcinoma, ovarian cancer, gastric cancer, and pancreatic cancer.
- Non-small cell lung cancer
- Breast cancer
- Colorectal cancer
- Renal cell carcinoma
- Urothelial carcinoma
Research also extends to molecularly selected tumors involving KRAS, EGFR, HER2, ALK, ROS1, FGFR, and IDH alterations.
Immune-mediated and autoimmune disease
Clinical activity includes systemic lupus erythematosus, cutaneous lupus erythematosus, rheumatoid arthritis, psoriatic arthritis, systemic sclerosis, Sjögren's disease, myasthenia gravis, and idiopathic inflammatory myopathy, together with other immune-mediated disorders.
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Myasthenia gravis
- Systemic sclerosis
- Idiopathic inflammatory myopathy
Additional involvement in immune thrombocytopenia, vasculitis, and autoimmune glomerular disease highlights interest in complex inflammatory conditions.
Respiratory, infectious, and transplant-related medicine
The investigator contributes to studies in asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, bronchiectasis, pulmonary hypertension, and sleep apnea, alongside work in infectious diseases and transplant medicine.
- Asthma
- Idiopathic pulmonary fibrosis
- Bronchiectasis
- Pulmonary hypertension
- Kidney transplantation
Research also touches opportunistic infections, viral hepatitis, and transplant rejection, linking respiratory and immunologic care with post-transplant management.
Cardiometabolic, renal, and neurologic disorders
Additional research areas include renal disease, proteinuric glomerular disorders, heart failure, atherosclerotic cardiovascular disease, diabetes mellitus, obesity, stroke, epilepsy, and migraine.
- Chronic kidney disease
- Heart failure
- Diabetes mellitus
- Stroke
- Migraine
There is also interest in amyloidosis, myelofibrosis, and metabolic liver disease, supporting a diverse therapeutic portfolio beyond oncology and immunology.
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