Patricia T. D.
- Country
- Spain
- Department
- Medical Oncology
Research Overview
- Phase 3 Study of Vepugratinib and Combination Therapy in Adults with Untreated FGFR3-Altered Locally Advanced or Metastatic Urothelial Carcinoma
- Phase 2 Open‑Label Single‑Arm Study of Enfortumab Vedotin Plus Pembrolizumab for Bladder Preservation in Patients with Muscle‑Invasive Bladder Cancer
- Phase 3 Randomized Double-Blind Study of Talazoparib and Enzalutamide in Metastatic Castration-Resistant Prostate Cancer
Data & Insights
Has run more than one trial at 30 of 161 partner sites.
Specializations
Hematologic Malignancies
Clinical research in multiple myeloma, chronic lymphocytic leukemia, small lymphocytic lymphoma, follicular lymphoma, marginal zone lymphoma, mantle cell lymphoma, and myelodysplastic syndrome, with additional activity in acute leukemias and high-risk monoclonal gammopathy.
- Relapsed and refractory disease
- Newly diagnosed plasma cell disorders
- Targeted and immune-based therapy
Work also extends to lymphoid neoplasms and treatment settings involving transplant eligibility and disease control in advanced blood cancers.
Solid Tumors and Genitourinary Oncology
Research interests include breast cancer, non-small cell lung cancer, prostate cancer, bladder cancer, upper tract urothelial carcinoma, pancreatic adenocarcinoma, and cervical cancer.
- Hormone receptor-positive breast cancer
- Metastatic prostate cancer
- Urothelial malignancies
The therapeutic focus includes advanced and localized disease management, perioperative treatment strategies, and biomarker-driven oncology.
Cardiovascular and Thrombotic Disease
Clinical activity covers acute myocardial infarction, acute coronary syndrome, atrial fibrillation, stroke prevention, atherosclerotic cardiovascular disease, hypertension, hypercholesterolemia, and mechanical valve anticoagulation.
- Secondary prevention after ischemic events
- Antithrombotic therapy
- Cardiovascular risk reduction
Additional interest is seen in transcatheter aortic valve implantation, cardio-renal complications, and inflammation-related vascular risk.
Inflammatory, Autoimmune, and Respiratory Disorders
Research spans asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, progressive fibrosing interstitial lung disease, pulmonary sarcoidosis, Crohn’s disease, ulcerative colitis, hidradenitis suppurativa, psoriasis, atopic dermatitis, urticaria, and systemic lupus erythematosus.
- Chronic inflammatory skin disease
- Inflammatory bowel disease
- Fibrotic and obstructive lung disease
There is also involvement in allergic rhinitis, eosinophilic esophagitis, and other immune-mediated conditions affecting the airway and gastrointestinal tract.
Neurology, Metabolic, and Infectious Disease
Clinical research includes Parkinson’s disease, multiple sclerosis, focal epilepsy, Alzheimer’s disease, thyroid eye disease, diabetes, chronic kidney disease, HIV infection, hepatitis B, and respiratory syncytial virus infection.
- Neurodegenerative disorders
- Metabolic and renal disease
- Viral and bacterial infections
Therapeutic interests also include migraine, pain syndromes, and immune-mediated neurologic disease.
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