Pasquale S.
- Country
- Belgium
- Department
- Department of Neurology
Research Overview
Data & Insights
Has run more than one trial at 0 of 70 partner sites.
Specializations
Neurovascular Disorders
The investigator focuses on conditions affecting cerebral blood flow and vessel integrity, aiming to improve outcomes after acute events.
- Acute ischemic stroke
- Intracerebral haemorrhage
- High‑risk transient ischemic attack
- Arterio‑venous malformations
Research integrates acute management strategies with secondary prevention.
Neurodegenerative Diseases
Efforts target progressive neuronal loss, with emphasis on early detection and disease‑modifying interventions.
- Alzheimer’s disease
- Parkinsonian syndromes
- Frontotemporal dementia
- Neurodegeneration associated with amyloid‑tau pathology
Clinical work includes biomarker validation and therapeutic exploration.
Neuroinflammatory & Autoimmune Neurology
Investigation of immune‑mediated disorders of the central and peripheral nervous system forms a core component of the program.
- Multiple sclerosis
- Neuromyelitis optica spectrum disorder
- Myasthenia gravis
- Chronic inflammatory demyelinating polyneuropathy
Therapeutic goals include modulation of pathogenic immune pathways.
Neuro‑Oncology
The investigator contributes to the study of primary and secondary brain tumors, emphasizing targeted and immunologic approaches.
- Glioblastoma
- Brain metastasis from breast cancer
- Medulloblastoma
- Primary central nervous system lymphoma
Clinical work integrates molecular profiling with novel therapeutic regimens.
Neuromuscular & Seizure Disorders
Research addresses disorders of muscle control and epileptic activity, seeking to enhance functional outcomes.
- Focal‑onset seizures
- Generalized tonic‑clonic seizures
- Peripheral neuropathies
- Motor neuron disease
Investigations span pharmacologic and device‑based interventions.
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